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硝甲西泮

硝甲西泮
临床资料
商品名英语Drug nomenclatureErimin
AHFS/Drugs.com国际药品名称
怀孕分级
  • X
给药途径口服 成瘾倾向:高
ATC码
法律规范状态
法律规范
药物动力学数据
生物利用度95%
药物代谢肝脏
生物半衰期14至30小时
排泄途径肾脏
识别信息
  • 1-methyl-7-nitro-5-phenyl-3H-1,4-benzodiazepin-2-one
CAS号2011-67-8  ☒N
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard英语CompTox Chemicals Dashboard (EPA)
ECHA InfoCard100.016.302 编辑维基数据链接
化学信息
化学式C16H13N3O3
摩尔质量295.3 g/mol
3D模型(JSmol英语JSmol
  • [O-][N+](C1=CC2=C(C=C1)N(C)C(CN=C2C3=CC=CC=C3)=O)=O
  • InChI=1S/C16H13N3O3/c1-18-14-8-7-12(19(21)22)9-13(14)16(17-10-15(18)20)11-5-3-2-4-6-11/h2-9H,10H2,1H3 checkY
  • Key:GWUSZQUVEVMBPI-UHFFFAOYSA-N checkY

硝甲西泮(Nimetazepam),又译硝甲氮平,其作用为中枢神经抑制剂[1]俗称一粒眠(Erimine),属中华民国三级管制性药品[2],又称“红豆”、“五仔”、“K它命5号”、“Give me Five”。

适应症

临床医学上,主要用来治疗焦虑失眠酒精戒断、肌肉紧缩等症状。

物质滥用

使用超过四星期,将产生药物依赖性、耐药性,且对人类记忆力与注意力形成障碍。若与其他药物或酒精一并服用,危害性增高。严重者死亡

参考文献

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硝甲西泮
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