喹唑啉酮
| 4-喹唑啉酮 | |
|---|---|
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| IUPAC名 Quinazolin-4(3H)-one | |
| 别名 | 4(3H)-Quinazolinone; 4(1H)-Quinazolinone; 3,4-Dihydroquinazolin-4-one; 4(3H)-Quinazolone; 4-Hydroxyquinazoline; 4-Oxo-3,4-dihydroquinazoline; 4-Oxoquinazoline; 4-Quinazolinol; 4-Quinazolinone; 4-Quinazolone |
| 识别 | |
| CAS号 | 491-36-1 
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| PubChem | 63112 |
| ChemSpider | 56797 |
| SMILES |
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| InChI |
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| 性质 | |
| 化学式 | C8H6N2O |
| 摩尔质量 | 146.15 g·mol−1 |
| 若非注明，所有数据均出自标准状态（25 ℃，100 kPa）下。 | |
喹唑啉酮（Quinazolinone）是喹唑啉的一类衍生物，通常指4-喹唑啉酮，是多种生物碱和药物的骨架结构。
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2-喹唑啉酮 -
4-喹唑啉酮
衍生物
喹唑啉酮类催眠/镇静药物有4-喹唑啉酮的核心结构，其应用已扩展到癌症治疗。[1]
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地普喹酮 -
含喹唑啉酮结构的生物碱例如吴茱萸碱，常山碱等。
参考资料
- ^ Chen K, Wang K, Kirichian AM; et al. In silico design, synthesis, and biological evaluation of radioiodinated quinazolinone derivatives for alkaline phosphatase-mediated cancer diagnosis and therapy. Mol. Cancer Ther. December 2006, 5 (12): 3001–13 [2013-08-30]. PMID 17172404. doi:10.1158/1535-7163.MCT-06-0465. （原始内容存档于2019-10-29）.
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