Metomidate
Chemical compound
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ECHA InfoCard | 100.023.971 |
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Formula | C13H14N2O2 |
Molar mass | 230.267 g·mol−1 |
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Metomidate is a non-barbiturate imidazole that was discovered by Janssen Pharmaceutica in 1965[1] and under the names (Hypnodil, Nokemyl) is sold as a sedative-hypnotic drug used in Europe to treat humans and for veterinary purposes.[2]
11C-labelled metomidate (11C-metomidate), may be used with positron emission tomography (PET). For instance, to detect tumors of adrenocortical origin.[3][4]
- ^ BE Patent 662474
- ^ Index nominum 2000: international drug directory. Taylor & Francis US. 2000. p. 683. ISBN 978-3-88763-075-1. Retrieved 27 October 2011.
- ^ Khan TS, Sundin A, Juhlin C, Långström B, Bergström M, Eriksson B (March 2003). "11C-metomidate PET imaging of adrenocortical cancer". European Journal of Nuclear Medicine and Molecular Imaging. 30 (3): 403–10. doi:10.1007/s00259-002-1025-9. PMID 12634969. S2CID 23744095.
- ^ Minn H, Salonen A, Friberg J, Roivainen A, Viljanen T, Långsjö J, et al. (June 2004). "Imaging of adrenal incidentalomas with PET using (11)C-metomidate and (18)F-FDG". Journal of Nuclear Medicine. 45 (6): 972–9. PMID 15181132.
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