Proxibarbital
Chemical compound
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| Other names | Proxibarbital, Centralgol, Ipronal, 5-Allyl-5-(β-hydroxypropyl)barbituric acid |
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| ECHA InfoCard | 100.018.004  |
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| Formula | C10H14N2O4 |
| Molar mass | 226.232 g·mol−1 |
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Proxibarbital (Ipronal) is a barbiturate derivative synthesized in 1956. It has anti-anxiety properties and is, in contrast to most barbiturates, almost without hypnotic action.[1]
It was also used in the treatment of migraine headaches in a similar manner to butalbital.[2]
Valofane isomerises to Proxibarbal in vivo.
- ^ Zajdel P, Kulig K, Zejc A (2008). Zejc A, Gorczyca M (eds.). Chemia leków, podręcznik dla studentów farmacji i farmaceutów [Drug chemistry, textbook for pharmacy students and pharmacists] (in Polish). Warszawa, Poland. ISBN 978-83-200-3652-7.
((cite book)): CS1 maint: location missing publisher (link) - ^ Sulman FG, Pfeifer Y, Tal E (December 1976). "[Migraine therapy by enzyme induction with proxibarbital]". Therapie der Gegenwart (in German). 115 (12): 2088–103. PMID 14412.
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