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Vinorelbine

Vinorelbine
Image illustrative de l’article Vinorelbine
Identification
Nom UICPA ester de 4-(acétyloxy)- 6,7-didéhydro- 15-((2R,6R,8S)-4-éthyl- 1,3,6,7,8,9-hexahydro- 8-(méthoxycarbonyl)- 2,6-méthano- 2H-azecino(4,3-b)indol-8-yl)- 3-hydroxy- 16-méthoxy- 1-méthyl-méthyle,
acide (2beta,3beta,4beta,5alpha,12R,19alpha)- aspidospermidine- 3-carboxylique
No CAS
Code ATC L01CA04
SMILES
InChI
Propriétés chimiques
Formule C45H54N4O8  [Isomères]
Masse molaire[1] 778,932 3 ± 0,043 g/mol
C 69,39 %, H 6,99 %, N 7,19 %, O 16,43 %,

Unités du SI et CNTP, sauf indication contraire.

La vinorelbine (Navelbine) est un agent anticancéreux (chimiothérapie) utilisé dans la plupart des pays du monde dans le traitement du cancer du poumon et du cancer du sein. Médicament issu de la recherche française (Centre national de la recherche scientifique et Laboratoires Pierre Fabre), elle est désormais administrée par voie orale, pour un plus grand confort et une plus grande facilité d'utilisation.

Notes et références

  1. Masse molaire calculée d’après « Atomic weights of the elements 2007 », sur www.chem.qmul.ac.uk.
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Vinorelbine
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