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Temsirolimus

Le temsirolimus est un médicament utilisé comme inhibiteur de la mammalian target of rapamycin (mTor).

Efficacité

Dans le cancer du rein métastatique, le temsirolimus s'avère être plus efficace, en particulier en termes de mortalité, par rapport à l’interféron[1].

Dans le lymphome du manteau, le temsirolimus obtient une réponse, essentiellement partielle entre 20[2] et 40 % des cas[3]. Il est cependant moins efficace que l'ibrutinib[4].

Effets secondaires

Il a une toxicité hématologique dans près de la moitié des cas[3], augmentant avec les doses utilisée[5].

  • Compendium suisse des médicaments : spécialités contenant Temsirolimus

Notes et références

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Temsirolimus
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