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头孢烯

头孢菌素的核心结构
头霉素的核心结构

头孢烯(英語:cephems)即2,3-脱氢头孢烷,是一类具有头孢菌素主核的不饱和β-内酰胺抗生素,其核心结构包括有一个β-内酰胺四元环和含硫的不饱和六元环,结构上分为头孢菌素头霉素两类,头霉素比头孢菌素多一个7号位置上的甲氧基[1][2]

参考文献

[编辑]
  1. ^ Chemical and Microbiologic Aspects of Penems. Medscape. [2021-11-10]. (原始内容存档于2021-11-10) (英语). 
  2. ^ Vitaku, Edon; Smith, David T.; Njardarson, Jon T. Analysis of the Structural Diversity, Substitution Patterns, and Frequency of Nitrogen Heterocycles among U.S. FDA Approved Pharmaceuticals: Miniperspective. Journal of Medicinal Chemistry. 2014-12-26, 57 (24): 10257–10274 [2021-11-10]. ISSN 0022-2623. doi:10.1021/jm501100b. (原始内容存档于2022-04-15) (英语). 
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头孢烯
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