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头孢唑兰

头孢唑兰
臨床資料
AHFS/Drugs.com国际药品名称
ATC碼
识别信息
  • (6R,7R)-7-[[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)- 2-methoxyiminoacetyl]amino]-3-(imidazo[2,3-f]pyridazin- 4-ium-1-ylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0] oct-2-ene-2-carboxylate
CAS号113359-04-9  checkY
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard英语CompTox Chemicals Dashboard (EPA)
ECHA InfoCard100.107.680 編輯維基數據鏈接
化学信息
化学式C19H17N9O5S2
摩尔质量515.52 g·mol−1
3D模型(JSmol英语JSmol
  • O=C2N1/C(=C(\CS[C@@H]1[C@@H]2NC(=O)C(=N\OC)/c3nc(sn3)N)Cn5c4cccn[n+]4cc5)C([O-])=O
  • InChI=1S/C19H17N9O5S2/c1-33-24-11(14-23-19(20)35-25-14)15(29)22-12-16(30)28-13(18(31)32)9(8-34-17(12)28)7-26-5-6-27-10(26)3-2-4-21-27/h2-6,12,17H,7-8H2,1H3,(H3-,20,22,23,25,29,31,32)/b24-11-/t12-,17-/m1/s1 ☒N
  • Key:QDUIJCOKQCCXQY-WHJQOFBOSA-N ☒N

头孢唑兰INN:Cefozopran)是第四代头孢菌素[1]

细菌敏感性和耐药性

[编辑]

大多数嗜麦芽寡养单胞菌英语Stenotrophomonas maltophilia菌株已对头孢唑仑产生耐药性。[2]

参考资料

[编辑]
  1. ^ Chang XM. Chapter 34: Market to Market. Bristol JA (编). Annual Reports in Medicinal Chemistry 31. San Diego, Calif.: Academic Press. December 1996: 339. ISBN 978-0-08-058375-4. 
  2. ^ Cefozopran Susceptibility and Resistance Data (PDF). [23 July 2013]. 
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头孢唑兰
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