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头孢维星

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头孢维星
臨床資料
懷孕分級
  • 繁殖和泌乳动物安全性不确定
给药途径皮下
ATCvet碼
法律規範狀態
法律規範
  • 兽医专用
藥物動力學數據
药物代谢不经肝脏代谢
生物半衰期狗5.5天;猫6.9天
排泄途徑主要从尿中以原形排泄
识别信息
  • (7R)-7-([(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino)-8-oxo-3-[(2S)-oxolan-2-yl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
CAS号234096-34-5  checkY
141195-77-9(钠盐)  ☒N
PubChem CID
CompTox Dashboard英语CompTox Chemicals Dashboard (EPA)
化学信息
化学式C17H19N5O6S2
摩尔质量453.49 g·mol−1
3D模型(JSmol英语JSmol
  • CON=C(C1=CSC(=N1)N)C(=O)NC2C3N(C2=O)C(=C(CS3)C4CCCO4)C(=O)O

头孢维星CefovecinINN),是第三代的头孢类抗菌药,用于治疗猫狗的皮肤感染,临床上使用钠盐。头孢维星由輝瑞旗下的碩騰公司(Zoetis)販售,商品名为Convenia康卫宁(中國大陸)、久安(臺灣)[1]

批准及使用

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头孢维星于2006年6月首次得到欧盟批准使用於犬、貓[2]。2008年6月,美国批准使用於犬、貓[3]。 14天一次的皮下注射為此抗生素的使用方式,適應症包括細菌引起之皮膚病(膿皮症)、泌尿道感染(UTI)或細菌性口炎,獸醫師可針對病情來調整使用的頻次,如七天一次。

参考文献

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  1. ^ 康卫宁. [2013-10-17]. (原始内容存档于2013-10-17). 
  2. ^ European Public Assessment Report for Convenia (from the EMEA website). [2008-07-11]. (原始内容存档于2008-08-04). 
  3. ^ FDA Approves First and Only Single-Dose Antibiotic for Dogs and Cats (新闻稿). Pfizer Inc. 2008-06-30 [2008-07-11]. (原始内容存档于2016-05-29). 

外部链接

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头孢维星
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