Profilin 1
Profilin-1 is a protein that in humans is encoded by the PFN1 gene.[5][6]
Function
The protein encoded by this gene is a ubiquitous actin monomer-binding protein belonging to the profilin family. It is thought to regulate actin polymerization in response to extracellular signals. Deletion of this gene is associated with Miller-Dieker syndrome.[7] Mutations in this gene may be a rare cause of amyotrophic lateral sclerosis, also called Lou Gehrig's disease.[8][9][10][11][12][13][14][15][16][17][18][19][20]
Interactions
Profilin 1 has been shown to interact with:
Text is available under the CC BY-SA 4.0 license; additional terms may apply.
Images, videos and audio are available under their respective licenses.