KRT78
Identifiers
Aliases	KRT78, CK-78, K5B, K78, Kb40, keratin 78
External IDs	OMIM: 611159; MGI: 1917529; HomoloGene: 65261; GeneCards: KRT78; OMA:KRT78 - orthologs
Gene location (Human) Chr. Chromosome 12 (human)[1] Band 12q13.13 Start 52,837,804 bp[1] End 52,849,092 bp[1]
Gene location (Mouse) Chr. Chromosome 15 (mouse)[2] Band 15|15 F2 Start 101,854,436 bp[2] End 101,862,722 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in buccal mucosa cell oral cavity mucosa of pharynx amniotic fluid skin of leg body of tongue gums skin of abdomen gingival epithelium testicle Top expressed in esophagus lip skin of external ear condyle conjunctival fornix fossa stomach skin of back cornea molar More reference expression data BioGPS n/a
Gene ontology Molecular function structural molecule activity Cellular component intermediate filament keratin filament extracellular exosome extracellular space cytosol Biological process keratinization cornification Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 196374 332131 Ensembl ENSG00000170423 ENSMUSG00000050463 UniProt Q8N1N4 n/a RefSeq (mRNA) NM_001300814 NM_173352 NM_212487 RefSeq (protein) NP_001287743 NP_775487 n/a Location (UCSC) Chr 12: 52.84 – 52.85 Mb Chr 15: 101.85 – 101.86 Mb PubMed search [3] [4]
Wikidata
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Keratin, type II cytoskeletal 78 is a protein that in humans is encoded by the KRT78 gene.^[5][6]

This gene is a member of the type II keratin gene family and encodes a protein with an intermediate filament domain. Keratins are the major structural proteins in epithelial cells, forming a cytoplasmic network of 10 to 12 nm wide intermediate filaments and creating a scaffold that gives cells the ability to withstand mechanical and non-mechanical stresses. The genes of the type II keratin family are located as a gene cluster at 12p13.13. Four pseudogenes of this gene family have been identified.^[6]