ZNF43
Identifiers
Aliases	ZNF43, HTF6, KOX27, ZNF39L1, zinc finger protein 43
External IDs	OMIM: 603972; MGI: 3040691; HomoloGene: 128170; GeneCards: ZNF43; OMA:ZNF43 - orthologs
Gene location (Human) Chr. Chromosome 19 (human)[1] Band 19p12 Start 21,804,946 bp[1] End 21,852,125 bp[1]
Gene location (Mouse) Chr. Chromosome 13 (mouse)[2] Band 13 B3|13 34.54 cM Start 67,254,918 bp[2] End 67,278,466 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in Achilles tendon ganglionic eminence ventricular zone corpus callosum testicle bone marrow cells gonad endometrium epithelium of colon tonsil Top expressed in Rostral migratory stream lumbar subsegment of spinal cord tail of embryo genital tubercle vestibular membrane of cochlear duct Region I of hippocampus proper ganglionic eminence vas deferens transitional epithelium of urinary bladder embryo More reference expression data BioGPS More reference expression data
Gene ontology Molecular function DNA-binding transcription factor activity DNA binding metal ion binding nucleic acid binding DNA-binding transcription factor activity, RNA polymerase II-specific Cellular component intracellular anatomical structure nucleus Biological process regulation of transcription, DNA-templated transcription, DNA-templated regulation of transcription by RNA polymerase II Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 7594 238690 Ensembl ENSG00000198521 ENSG00000279566 ENSMUSG00000055480 UniProt P17038 Q6P5C7 RefSeq (mRNA) NM_001256648 NM_001256649 NM_001256650 NM_001256651 NM_001256653 NM_001256654 NM_003423 NM_001001152 RefSeq (protein) NP_001243577 NP_001243578 NP_001243579 NP_001243580 NP_001243582 NP_001243583 NP_003414 NP_001243577.1 NP_001243578.1 NP_001243579.1 NP_001001152 Location (UCSC) Chr 19: 21.8 – 21.85 Mb Chr 13: 67.25 – 67.28 Mb PubMed search [3] [4]
Wikidata
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Zinc finger protein 43 is a protein that in humans is encoded by the ZNF43 gene.^[5][6]

Function

This gene belongs to the C2H2-type zinc finger gene family. The zinc finger proteins are involved in gene regulation and development, and are quite conserved throughout evolution. Like this gene product, a third of the zinc finger proteins containing C2H2 fingers also contain the KRAB domain, which has been found to be involved in protein-protein interactions.^[6]