BRN-3
| POU class 4 homeobox 1 | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Symbol | POU4F1 | ||||||
| Alt. symbols | BRN3A | ||||||
| NCBI gene | 5457 | ||||||
| HGNC | 9218 | ||||||
| OMIM | 601632 | ||||||
| RefSeq | NM_006237 | ||||||
| UniProt | Q01851 | ||||||
| Other data | |||||||
| Locus | Chr. 13 q31.1 | ||||||
| |||||||
| POU class 4 homeobox 2 | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Symbol | POU4F2 | ||||||
| Alt. symbols | BRN3B | ||||||
| NCBI gene | 5458 | ||||||
| HGNC | 9219 | ||||||
| OMIM | 113725 | ||||||
| RefSeq | NM_004575 | ||||||
| UniProt | Q12837 | ||||||
| Other data | |||||||
| Locus | Chr. 4 q31.22 | ||||||
| |||||||
| POU class 4 homeobox 3 | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Symbol | POU4F3 | ||||||
| Alt. symbols | BRN3C, DFNA15 | ||||||
| NCBI gene | 5459 | ||||||
| HGNC | 9220 | ||||||
| OMIM | 602460 | ||||||
| RefSeq | NM_002700 | ||||||
| UniProt | Q15319 | ||||||
| Other data | |||||||
| Locus | Chr. 5 q32 | ||||||
| |||||||
BRN-3 is a group of related transcription factors in the POU family.[1] They are also known as class 4 POU domain homeobox proteins.
There are three BRN-3 proteins encoded by the following genes:
Nomenclature
[edit]The BRN or Brn prefix is an abbreviation for "brain"; the longer name is "Brain-specific homeobox". The name of the group may also be abbreviated as POU4, Pou4, POU IV, or POU-IV.
References
[edit]- ^ Xiang M, Zhou L, Macke JP, Yoshioka T, Hendry SH, Eddy RL, Shows TB, Nathans J (1995). "The Brn-3 family of POU-domain factors: primary structure, binding specificity, and expression in subsets of retinal ganglion cells and somatosensory neurons". J. Neurosci. 15 (7 Pt 1): 4762–85. doi:10.1523/JNEUROSCI.15-07-04762.1995. PMC 6577904. PMID 7623109.
External links
[edit]- Transcription+Factor+Brn-3 at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
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