氨基青霉素
氨基青霉素（aminopenicillins）是一群β-内酰胺类抗生素青霉素的衍生物。氨基青霉素类因为在青霉素侧链的α位碳原子上加上了一个氨基（-NH2）而得名，第一种合成的氨基青霉素是氨苄西林。因为加上了一个氨基，氨基青霉素在酸性环境下稳定性增强，同时对革兰氏阴性菌的杀伤作用也增强，比如氨苄西林就对大肠杆菌等革兰氏阴性菌有杀伤作用[1][2]:214。
参见
[编辑]参考文献
[编辑]- ^ Cunha BA. Aminopenicillins in urology. Urology. August 1992, 40 (2): 186–90 [2018-07-06]. PMID 1502761. doi:10.1016/0090-4295(92)90525-2. （原始内容存档于2019-12-06）.
- ^ Roger G. Finch; et al. Antibiotic and Chemotherapy 9th edition. Elsevier. 2010. ISBN 978-0-7020-4064-1.
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