头孢尼西
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| 临床资料 | |
|---|---|
| AHFS/Drugs.com | Micromedex详细消费者药物信息 |
| MedlinePlus | a601206 |
| ATC码 | |
| 识别信息 | |
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| CAS号 | 61270-58-4 |
| PubChem CID | |
| ChemSpider | |
| UNII | |
| KEGG | |
| ChEBI | |
| ChEMBL | |
| CompTox Dashboard (EPA) | |
| 化学信息 | |
| 化学式 | C18H18N6O8S3 |
| 摩尔质量 | 542.56 g·mol−1 |
| 3D模型（JSmol） | |
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头孢尼西（英语：Cefonicide或Cefonicid）是头孢菌素抗生素。[1]
合成
[编辑]与头孢孟多相关的注射用半合成头孢菌素抗生素，q.v.
通过用适当取代的四唑硫醇 (2) 亲核置换 (1) 的 3-乙酰氧基部分可以方便地合成头孢尼西。扁桃酸酰胺C-7侧链让人联想到头孢孟多。
参见
[编辑]参考资料
[编辑]- ^ Saltiel E, Brogden RN. Cefonicid. A review of its antibacterial activity, pharmacological properties and therapeutic use. Drugs. September 1986, 32 (3): 222–59. PMID 3530703. S2CID 243051006. doi:10.2165/00003495-198632030-00002.
- ^ DE 2611270,Berges, David Alan,“Cephalosporin-Derivate [Cephalosporin derivatives]”,发表于1976-09-30
- ^ D. A. Berges, 美国专利第4,048,311号 (1977 to Smith Kline).
- ^ 美国专利第4,093,723号, 美国专利第4,159,373号 (1978, 1979 both to Smith Kline).
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