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苄基

苄基

biàn(英語:benzyl,benzyl group)又稱苯甲基,是有机化学中具有 R–CH
2
–C
6
H
5
结构的取代基或分子片段,即甲苯甲基上的氢被去掉后形成的基团。苄基具有一个连接亚甲基(–CH
2
–)的苯环(C
6
H
6
[1]有机合成中,苄基缩写为Bn。

有机合成中苄基被用于保护羟基,包括羧酸

上苄基:在碱水(例如:碳酸钾)和二氯甲烷体系中缓慢滴入溴化苄,加热至30~40度。

脱苄基:H2/Pd 50Psi氢化,或者用硫酸

参见

[编辑]

參考

[编辑]
  1. ^ Carey, F. A.; Sundberg, R. J. Advanced Organic Chemistry, Part A: Structure and Mechanisms有限度免费查阅,超限则需付费订阅 5th. New York, NY: Springer. 2008: 806–808, 312–313. ISBN 9780387448978. 
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苄基
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