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真核延伸因子

真核延伸因子有两种:真核延伸因子1(eEF-1)和真核延伸因子2(eEF-2)。

  • 真核延伸因子1 eEF-1 由两个亚基组成: α 和βγ。α亚基相当于原核的延伸因子EF-Tu,介导氨酰tRNA进入核糖体的A位。βγ亚基相当于原核的延伸因子EF-Ts,作为 α亚基的鳥嘌呤核苷酸交换因子英语nucleotide exchange factor,催化α亚基上GDP的释放。
  • 真核延伸因子2 eEF-2 相当于原核的延伸因子EF-G,催化tRNA和mRNA从核糖体的A位进入P位,使肽链延长。

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真核延伸因子
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