非特异性间质性肺炎
非特异性间质性肺炎（Non-specific interstitial pneumonia，简称NSIP）属于一种特发性间质性肺炎。
症状
[编辑]病因
[编辑]目前认为属于一种自体免疫有关，可能为未分化型结缔组织疾病的并发症[2]。
分类
[编辑]NSIP可依病理切片分为细胞性及纤维性两种，两种以预后不同。细胞性的镜检会显示慢性发炎但纤维化较少的情形；纤维性则会显示间质性纤维化，且发炎状态不一。在其他种类的特发性肺炎一般有一个明显的点状纤维化区域，但在NSIP中没有这种情形，一般为一整片的纤维化[3]。
预后
[编辑]纤维性NSIP的五年存活率约于 86% 至 92%之间，细胞性则为 100% 。大体来说NSIP的预后较寻常性间质性肺炎（UIP）为佳[4]。
参考文献
[编辑]- ^ Cottin, Vincent, et al. "Nonspecific interstitial pneumonia: individualization of a clinicopathologic entity in a series of 12 patients." American journal of respiratory and critical care medicine 158.4 (1998): 1286-1293.
- ^ Kinder, Brent W., et al. "Idiopathic nonspecific interstitial pneumonia: lung manifestation of undifferentiated connective tissue disease?." American journal of respiratory and critical care medicine 176.7 (2007): 691-697.
- ^ Travis, William D., et al. "Idiopathic nonspecific interstitial pneumonia: report of an American Thoracic Society project." American journal of respiratory and critical care medicine 177.12 (2008): 1338-1347.
- ^ Travis, William D., et al. "Idiopathic nonspecific interstitial pneumonia: prognostic significance of cellular and fibrosing patterns: survival comparison with usual interstitial pneumonia and desquamative interstitial pneumonia." The American journal of surgical pathology 24.1 (2000): 19-33.
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