For faster navigation, this Iframe is preloading the Wikiwand page for CCL18.

CCL18

Hemokin (C-C motiv) ligand 18
Identifikatori
SimbolCCL18
Alt. simboliSCYA18, DC-CK1, PARC, AMAC-1, DCCK1, MIP-4, CKb7
Entrez6362
HUGO10616
OMIM603757
RefSeqNM_002988
UniProtP55774
Ostali podaci
LokusHromozom 17 q11.2

CCL18, hemokin (C-C motiv) ligand 18, je mali citokin iz CC hemokin familije koja je ranije zvao PARC (pulmonarno i activacijom-regulisani hemokin). CCL18 je približno 60% identičan u aminokiselinskoj sekvenci sa CCL3. On je izražen u visokim nivoima u plućima i u niskim nivoima u pojedinim limfoidnim tkivima, kao što su limfni čvorovi. CCL18 je hemotaksan za aktivirane T ćelije i neaktivirane limfocite.[1] Ljudski CCL18 gen sadrži tri eksona i lociran je na hromozomu 17.[1][2][3]

  1. ^ а б Hieshima K, Imai T, Baba M, Shoudai K, Ishizuka K, Nakagawa T, Tsuruta J, Takeya M, Sakaki Y, Takatsuki K, Miura R, Opdenakker G, Van Damme J, Yoshie O, Nomiyama H (1997). „A novel human CC chemokine PARC that is most homologous to macrophage-inflammatory protein-1 alpha/LD78 alpha and chemotactic for T lymphocytes, but not for monocytes”. Journal of Immunology. 159 (3): 1140—9. PMID 9233607. 
  2. ^ Tasaki, Y. (1999). „Chemokine PARC Gene (SCYA18) Generated by Fusion of Two MIP-1α/LD78α-like Genes,”. Genomics. 55: 353—357. PMID 10049593. doi:10.1006/geno.1998.5670. 
  3. ^ Mire-Sluis, Anthony R.; Thorpe, Robin, ур. (1998). Cytokines (Handbook of Immunopharmacology). Boston: Academic Press. ISBN 0-12-498340-5. 

Spoljašnje veze

[уреди | уреди извор]
{{bottomLinkPreText}} {{bottomLinkText}}
CCL18
Listen to this article

This browser is not supported by Wikiwand :(
Wikiwand requires a browser with modern capabilities in order to provide you with the best reading experience.
Please download and use one of the following browsers:

This article was just edited, click to reload
This article has been deleted on Wikipedia (Why?)

Back to homepage

Please click Add in the dialog above
Please click Allow in the top-left corner,
then click Install Now in the dialog
Please click Open in the download dialog,
then click Install
Please click the "Downloads" icon in the Safari toolbar, open the first download in the list,
then click Install
{{::$root.activation.text}}

Install Wikiwand

Install on Chrome Install on Firefox
Don't forget to rate us

Tell your friends about Wikiwand!

Gmail Facebook Twitter Link

Enjoying Wikiwand?

Tell your friends and spread the love:
Share on Gmail Share on Facebook Share on Twitter Share on Buffer

Our magic isn't perfect

You can help our automatic cover photo selection by reporting an unsuitable photo.

This photo is visually disturbing This photo is not a good choice

Thank you for helping!


Your input will affect cover photo selection, along with input from other users.

X

Get ready for Wikiwand 2.0 🎉! the new version arrives on September 1st! Don't want to wait?