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米诺环素

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米诺环素
臨床資料
给药途径口服
ATC碼
法律規範狀態
法律規範
藥物動力學數據
生物利用度100%
药物代谢肝脏
生物半衰期11-22 hours
排泄途徑主要为粪便、剩余为尿液
识别信息
  • 4,7-双(二甲氨基)-1,4,4a,5,5a,6,11,12a-八氢-3,10,12,12a-四羟基-1,11-二氧-2-并四苯甲酰胺
CAS号10118-90-8  checkY
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard英语CompTox Chemicals Dashboard (EPA)
ECHA InfoCard100.226.626 編輯維基數據鏈接
化学信息
化学式C23H27N3O7
摩尔质量457.477

米诺环素又称“二甲胺四环素”或“美满环素”,是一种广谱抗菌的四环素类抗生素。它能与tRNA结合,从而达到抑菌的效果。米诺环素比同类药物具有更广的抗菌谱,具有抑菌活性。因为其半衰期较长,米诺环素的血药浓度比其他同类型药物高2至4倍。

适应症

[编辑]

米诺环素主要用于治疗痤疮和其他皮肤感染,由于半衰期长,给药次数较其他药物少,使用方便。 尽管米诺环素具有广谱抗菌作用,但由于其副作用,应用受到很大限制。

副作用

[编辑]
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米诺环素
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