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酰胺醇类抗生素

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酰胺醇类抗生素是一种抗生素。常见的有得氯霉素甲砜霉素氟苯尼考等。临床常用的品种为甲砜霉素和氟苯尼考。制剂有甲砜霉素片、氟苯尼考注射液、氟苯尼考可溶性粉等。

抗菌机理

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抗菌机理是药物不可逆地结合于细菌核糖体50S亚基的受体部位,阻断肽酰基转移,抑制肽链延伸,干扰蛋白质合成,而产生抗菌作用。属抑菌性广谱抗生素,髙浓度时有杀菌作用。本类药物对革兰氏阴性菌的作用较革兰氏阳性菌强,对肠杆菌尤其是伤寒、副伤寒杆菌高度敏感。

参考文献

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https://iask.sina.com.cn/b/6i8AfILxrhN.html页面存档备份,存于互联网档案馆

https://iask.sina.com.cn/b/6dMmH4OZXqP.html页面存档备份,存于互联网档案馆


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酰胺醇类抗生素
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