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前列环素

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前列环素
臨床資料
AHFS/Drugs.comMonograph
ATC碼
识别信息
  • (Z)-5-[(4R,5R)-5-hydroxy-4-((S,E)-3-hydroxyoct-1-enyl)hexahydro-2H-cyclopenta[b]furan-2-ylidene]pentanoic acid
CAS号35121-78-9  checkY
PubChem CID
DrugBank
ChEMBL
CompTox Dashboard英语CompTox Chemicals Dashboard (EPA)
化学信息
化学式C20H32O5
摩尔质量352.465 g/mol
3D模型(JSmol英语JSmol
  • OC(=O)CCC\C=C1\C[C@@H]2[C@@H](/C=C/[C@@H](O)CCCCC)[C@H](O)C[C@@H]2O1

前列环素[1](英語:Prostacyclin,简称为PGI2)是脂类类花生酸家族中的一个成员,分子中有一个次级五元环,其前体是花生四烯酸或其他二十碳不饱和脂肪酸。前列环素会抑制血小板介导的凝集过程并有强烈的血管舒张作用,因此在凝血作用中,受损血管内皮的前列环素生成量会减少,这有利于血小板的聚集。

参考文献

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前列环素
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