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鹎冠状病毒HKU11

鹎冠状病毒HKU11
病毒分类 编辑
(未分级) 病毒 Virus
域: 核糖病毒域 Riboviria
界: 正核糖病毒界 Orthornavirae
门: 小核糖病毒门 Pisuviricota
纲: 小南嵌套病毒纲 Pisoniviricetes
目: 套式病毒目 Nidovirales
科: 冠状病毒科 Coronaviridae
属: 丁型冠状病毒属 Deltacoronavirus
种:
鹎冠状病毒HKU11 Bulbul coronavirus HKU11

鹎冠状病毒HKU11(Bulbul coronavirus HKU11、Bulbul-CoV HKU11)是丁型冠状病毒属的一种病毒,于2009年由香港大学的研究团队发表,此病毒在香港鸟类样本的普查中,从白头翁红耳鹎的样本中被发现,其基因组约长26500nt,是冠状病毒中基因组大小最小的病毒之一。此病毒的转录调控序列(transcription regulatory sequence、TRS)为5′-ACACCA-3′,和同属的鸫冠状病毒HKU12(Thrush CoV HKU12)及文鸟冠状病毒HKU13(Munia coronavirus HKU13)的TRS相同。除了冠状病毒皆有的复制酶与四种结构蛋白外,这三种病毒还有NS6、NS7a、NS7b与NS7c四种辅助蛋白,其中NS6、、NS7a与NS7c序列的前方不具有TRS。[1][2]

参考文献

[编辑]
  1. ^ Woo, P.C.; Lau, S.K.; Lam, C.S.; Lai, K.K.; Huang, Y.; Lee, P.; Luk, G.S.; Dyrting, K.C.; Chan, K.H.; Yuen, K.Y. Comparative analysis of complete genome sequences of three avian coronaviruses reveals a novel group 3c coronavirus. J. Virol. 2008, 83 (2): 908–917. PMC 2612373可免费查阅. PMID 18971277. doi:10.1128/jvi.01977-08. 
  2. ^ Woo, PC; Lau, SK; Lam, CS; Lau, CC; Tsang, AK; Lau, JH; Bai, R; Teng, JL; Tsang, CC; Wang, M; Zheng, BJ; Chan, KH; Yuen, KY. Discovery of seven novel Mammalian and avian coronaviruses in the genus deltacoronavirus supports bat coronaviruses as the gene source of alphacoronavirus and betacoronavirus and avian coronaviruses as the gene source of gammacoronavirus and deltacoronavirus. J Virol. Apr 2012, 86 (7): 3995–4008. PMC 3302495可免费查阅. PMID 22278237. doi:10.1128/JVI.06540-11. 
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鹎冠状病毒HKU11
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