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葡萄糖1-脱氢酶

葡萄糖1-脱氢酶
Glucose dehydrogenase tetramer, Caenorhabditis Elegans
识别码
EC编号 1.1.1.47
CAS号 9028-53-9
数据库
IntEnz IntEnz浏览
BRENDA英语BRENDA BRENDA入口
ExPASy英语ExPASy NiceZyme浏览
KEGG KEGG入口
MetaCyc英语MetaCyc 代谢路径
PRIAM英语PRIAM_enzyme-specific_profiles 概述
PDB RCSB PDB PDBj PDBe PDBsum
基因本体 AmiGO / EGO

葡萄糖1-脱氢酶(英语:glucose 1-dehydrogenaseEC 1.1.1.47页面存档备份,存于互联网档案馆))是一种以NAD+NADP+受体、作用于供体CH-OH基团上的氧化还原酶。这种催化以下酶促反应

β-D-葡萄糖 + NAD(P)+ D-葡萄糖酸-1,5-内酯 + NAD(P)H + H+

葡萄糖1-脱氢酶主要参与磷酸戊糖途径。这种酶也能氧化D-木糖。

结构研究

[编辑]

至2007年末,这类酶已被解析出9个三级结构,其PDB编码分别为1G6K1GCO1GEE1RWB1SPX2B5V2B5W2CD9以及2CDA

参考文献

[编辑]
  • K, Rick W, Staudinger HJ. A glucose dehydrogenase for the determination of glucose concentrations in body fluids (author's transl). Z. Klin. Chem. Klin. Biochem. 1975, 13 (3): 101–7. PMID 810982. 
  • Brink NG; Miettinen, Jorma K.; Olsen, John; Virtanen, Artturi I.; Sörensen, Nils Andreas. Beef liver glucose dehydrogenase. 1. Purification and properties. Acta Chem. Scand. 1953, 7: 1081–1089. doi:10.3891/acta.chem.scand.07-1081. 
  • Pauly HE and Pfleiderer G. D-Glucose dehydrogenase from Bacillus megaterium M 1286: purification, properties and structure. Hoppe-Seyler's Z. Physiol. Chem. 1976, 356 (10): 1613–1623. PMID 2530. 
  • Strecker HJ, Korkes S. Glucose dehydrogenase. J. Biol. Chem. 1952, 196 (2): 769–84. PMID 12981017. 
  • Thompson RE, Carper WR. Glucose dehydrogenase from pig liver. I. Isolation and purification. Biochim. Biophys. Acta. 1970, 198 (3): 397–406. PMID 4392298. 
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葡萄糖1-脱氢酶
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