核小体
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核小体（英语：Nucleosome，也译作核体或核仁小体）是组成真核生物染色质（除精子染色质外）的基本单位。
核小体是由DNA与4对组蛋白（共8个）组成的复合物，其中有H2A和H2B的二聚体两组以及H3和H4的二聚体两组。另外还有一种H1负责连结两个核小体之间的DNA。
参见
- 前核小体
参考文献
- ^ AL and Olins DE, "Spheroid Chromatin Units (nu Bodies)" （页面存档备份，存于互联网档案馆）, Science (1974); 183: 330 - 332
- ^ McDonald D, "Milestone 9, (1973-1974) The nucleosome hypothesis: An alternative string theory", Nature Milestones: Gene Expression. (2005) Dec 1; http://www.nature.com/milestones/geneexpression/milestones/articles/milegene09.html （页面存档备份，存于互联网档案馆）
- ^ Kornberg, RD, "Chromatin structure: a repeating unit of histones and DNA", Science. (1974); 184: 868–871
外部链接
- Nucleosomes on the group page of Timothy Richmond
- 蛋白质数据库中有关核小体的资料
- Dynamic Remodeling of Individual Nucleosomes Across a Eukaryotic Genome in Response to Transcriptional Perturbation
- Catalog of servers with experimental data and prediction tools for nucleosome positioning （页面存档备份，存于互联网档案馆）
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