SL-75102
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| Nazivi | |
|---|---|
| IUPAC naziv
4-[[(4-Hlorofenil)-(3-fluoro-6-oksocikloheksa-2,4-dien-1-iliden)metil]amino]butanoinska kiselina
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| Drugi nazivi
Progabidna kiselina; LS-187121; SL-75-102-00
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| Identifikacija | |
3D model (Jmol)
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| ChEBI | |
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| Svojstva | |
| C17H15ClFNO3 | |
| Molarna masa | 335,76 g·mol−1 |
Ukoliko nije drugačije napomenuto, podaci se odnose na standardno stanje materijala (na 25 °C [77 °F], 100 kPa). | |
| Reference infokutije | |
SL-75102, ili progabidna kiselina, je aktivni metabolit progabida i antikonvulsantni agonist GABA receptora .[3][4]
Reference
[уреди | уреди извор]- ^ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today. 15 (23-24): 1052—7. PMID 20970519. doi:10.1016/j.drudis.2010.10.003.
- ^ Evan E. Bolton; Yanli Wang; Paul A. Thiessen; Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry. 4: 217—241. doi:10.1016/S1574-1400(08)00012-1.
- ^ „Progabide and SL 75102 binding to plasma proteins and red blood cells in humans”. Int J Clin Pharmacol Ther Toxicol. 25 (4): 178—84. 1987. PMID 3583466.
- ^ „Anticonvulsant effect of SL 75 102 in adult and immature rats”. Physiol Res. 46 (1): 73—6. 1997. PMID 9728525.
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