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Kidd血型系统.
Kidd血型系统是人类血型系统之一。决定该系统血型分型的抗原称为Kidd抗原(Kidd antigens)或Jk抗原(Jk antigens)。
1951年,Allen等在一个姓Kidd的妇女血清中发现了一中新抗体,导致胎儿发生溶血性黄疸。该抗体对应的抗原被命名为Jka,这种血型系统则被命名为Kidd血型系统[1]。1953年,Plaut等又发现了Jka对应的抗原Jkb[2]。
Kidd血型系统的决定基因位于18号染色体(18q12.3)的JK基因。该基因有一对共显性等位基因Jka和Jkb,分别编码抗原Jka和Jkb。
- ^ Allen FH, Diamond LK, Niedziela B. A new blood-group antigen. Nature. 1951, 167: 482.
- ^ Plaut G, Ikin EW, Mourant AE; et al. A new blood-group antibody. Nature. 1953, 171: 431.
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