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間質性膀胱炎

間質性膀胱炎
Interstitial cystitis
类型膀胱炎urologic chronic pelvic pain syndrome[*]疾病
分类和外部资源
醫學專科泌尿外科
ICD-11GC00.3
ICD-10N30.1
ICD-9-CM595.1
DiseasesDB30832
MedlinePlus000477
eMedicinemed/2866
Orphanet37202
[编辑此条目的维基数据]

間質性膀胱炎(Interstitial cystitis,IC)屬於一種膀胱疼痛綜合症(Bladder pain syndrome, BPS),是一種原因不明的膀胱疾病,症狀是頻尿(通常每10分鐘一次)、尿急、骨盆或是膀胱感到極大壓力與疼痛、進行性行為時也會感受到極大疼痛[1]。上述兩者常合稱並縮寫為 IC/BPS[2],但由於醫學的進步,間質性膀胱炎這個術語已被質疑[3][4],目前將 IC/BPS 再歸類于“泌尿系慢性盆腔疼痛综合征[5][6][7](UCPPS)的一種。

由於頻繁的尿急感,間質性膀胱炎患者的生活品質大受影響,常常引發憂鬱症。統計上也發現間質性膀胱患者,也常患有大腸激躁症纖維肌痛症[8][9]

間質性膀胱炎的成因至今不明[1][9]。間質性膀胱炎通常不會造成家族性的遺傳。通常基於臨床症狀,在排除其他可能性後會做出間質性膀胱炎的診斷間質性膀胱炎的尿液結果通常不會有特定發現。膀胱镜檢查結果可能會發現潰瘍與發炎[8]。其他類似症狀的疾病,像是:泌尿道感染、性相關傳染疾病、膀胱過動症子宮內膜異位膀胱癌或是前列腺炎[9][10]。吸食K他命也會導致間質性膀胱炎[11],許多藥物濫用者甚至需要終身包尿布,嚴重影響社交行為。由於K他命在青少年族群間的藥物濫用有增加的趨勢,是目前需要關注的重點。

目前間質性膀胱炎還沒有特定的治療方式。改變生活型態、藥物或是手術都是可能有效的治療方式。常見的生活型態改變包括戒菸或是減少壓力。常見藥物治療包括布洛芬戊聚醣多硫酸酯英语pentosan polysulfate或是阿米替林。手術治療則包括膀胱撐開手術、神經刺激英语Neuromodulation_(medicine)以及膀胱替換手術[9]骨盆肌肉訓練或是長期使用抗生素治療的方式則並不鼓勵[8]

在美國和歐洲,經估計大約有0.5%的人口,受到間質性膀胱炎的困擾[8] [9]。女性罹患此疾病的比例是男性的五倍[9]。多數在中年的時候發病。此疾病初次於1887年出現在文獻之中[12]

參考文獻

  1. ^ 1.0 1.1 The Interstitial Cystitis Survival Guide: Your Guide to the Latest Treatment Options and Coping Strategies ISBN 1-57224-210-8
  2. ^ 存档副本. [2021-12-13]. (原始内容存档于2021-12-13). 
  3. ^ 存档副本. [2021-12-13]. (原始内容存档于2021-12-13). 
  4. ^ 存档副本. [2021-12-13]. (原始内容存档于2021-12-13). 
  5. ^ Adamian L, Urits I, Orhurhu V, Hoyt D, Driessen R, Freeman JA, Kaye AD, Kaye RJ, Garcia AJ, Cornett EM, Viswanath O. A Comprehensive Review of the Diagnosis, Treatment, and Management of Urologic Chronic Pelvic Pain Syndrome. Curr Pain Headache Rep. May 2020, 24 (6): 27. PMID 32378039. S2CID 218513050. doi:10.1007/s11916-020-00857-9. 
  6. ^ [1]俞旭君,高庆和.慢性前列腺炎中西医结合多学科诊疗指南[J].中华男科学杂志,2020,26(04):369-376.DOI:10.13263/j.cnki.nja.2020.04.015.
  7. ^ 存档副本. [2021-12-13]. (原始内容存档于2021-12-13). 
  8. ^ 8.0 8.1 8.2 8.3 Hanno, Philip M.; Erickson, Deborah; Moldwin, Robert; Faraday, Martha M.; American Urological Association. Diagnosis and treatment of interstitial cystitis/bladder pain syndrome: AUA guideline amendment. The Journal of Urology. 2015-5, 193 (5): 1545–1553 [2019-04-27]. ISSN 1527-3792. PMID 25623737. doi:10.1016/j.juro.2015.01.086. (原始内容存档于2020-04-16). 
  9. ^ 9.0 9.1 9.2 9.3 9.4 9.5 Interstitial cystitis/bladder pain syndrome fact sheet. OWH. 16 July 2012 [6 October 2016]. (原始内容存档于2016-10-05). 
  10. ^ Bogart, Laura M.; Berry, Sandra H.; Clemens, J. Quentin. Symptoms of interstitial cystitis, painful bladder syndrome and similar diseases in women: a systematic review. The Journal of Urology. 2007-2, 177 (2): 450–456 [2019-04-27]. ISSN 0022-5347. PMID 17222607. doi:10.1016/j.juro.2006.09.032. (原始内容存档于2020-04-12). 
  11. ^ ScienceDirect. www.sciencedirect.com. [2019-04-27]. 
  12. ^ Bostwick, David G.,; Cheng, Liang,. Urologic surgical pathology Third edition. Philadelphia, PA. [2019-04-27]. ISBN 9780323086196. OCLC 870868351. (原始内容存档于2019-07-13). 

外部連結

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間質性膀胱炎
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