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神经通路.
神经通路(英文:Neural pathway),是指一处神经元与另一处神经元之间的连接通路,由轴突、突触等组成,可传递神经系统的信号[1]。神经元之间可由单个轴突连接,也可由含多个轴突的神经径(中枢神经系统)或神经束(周围神经系统)连接[2]。较短的神经通路存在于脑灰质中,较长的通路包含髓磷脂(髓鞘)、构成白质。
锥体束中的下行神经通路(运动)自大脑皮层起连接至脑干或脊髓,而背柱-内侧丘系中的上行神经通路(感觉)将感官信息传递至大脑皮层[3][4]。
参考资料
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| 感覺/ 上行徑路 | PCML | 1°: |
- 帕西尼氏小体/触觉小体 → Posterior column (Gracile fasciculus/Cuneate fasciculus) → Gracile nucleus/Cuneate nucleus
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| 2°: |
- → sensory decussation/arcuate fibers (Posterior external arcuate fibers、Internal arcuate fibers) → Medial lemniscus/Trigeminal lemniscus → 丘脑 (VPL、VPM)
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| 3°: |
- → Posterior limb of internal capsule → 中央后回
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| 前外側系統/ 痛覺 | 快速徑路/外側 |
- 1° (Free nerve ending → A delta fiber) → 2° (Anterior white commissure → Lateral and Anterior 脊髓丘腦束 → 脊髓丘腦束 → VPL of 丘脑) → 3° (中央后回) → 4° (Posterior parietal cortex)
2° (Spinomesencephalic tract → Superior colliculus of Midbrain tectum)
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| 慢速徑路/內側 | |
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| 運動/ 下行徑路 | 錐體徑 |
- flexion: 初级运动皮层 → Posterior limb of internal capsule → Decussation of pyramids → 皮質脊髓徑 (Lateral, Anterior) → 神经肌肉接点
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| Extrapyramidal | flexion: | |
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| flexion: |
- Red nucleus → Rubrospinal tract
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| extension: | |
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| extension: | |
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- Midbrain tectum → Tectospinal tract → 頸部肌肉
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| 基底核 | direct: | |
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| indirect: | 1° ( 运动皮层 → 纹状体) → 2° ( GPe) → 3° ( Subthalamic fasciculus → Subthalamic nucleus) → 4° ( Subthalamic fasciculus → GPi) → 5° ( Lenticular fasciculus/ Ansa lenticularis → Thalamic fasciculus → VL of 丘脑) → 6° ( Thalamocortical radiations → Supplementary motor area) → 7° ( 运动皮层) |
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| nigrostriatal pathway: | |
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| 小脑 | Afferent |
- Pontine nuclei → Pontocerebellar fibers → MCP → 小脑深部核团 → Granule cell
- 下橄榄核 → Olivocerebellar tract → ICP → Hemisphere → Purkinje cell → 小脑深部核团
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| Efferent |
- Dentate nucleus in Lateral hemisphere/pontocerebellum → SCP → Dentatothalamic tract → 丘脑 (VL) → 运动皮层
- Interposed nucleus in Intermediate hemisphere/spinocerebellum → SCP → Reticular formation, or → Cerebellothalamic tract → Red nucleus → 丘脑 (VL) → 运动皮层
- Fastigial nucleus in Flocculonodular lobe/vestibulocerebellum → Vestibulocerebellar tract → Vestibular nuclei
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| Bidirectional: Spinocerebellar | 無意識本體感覺 |
- lower limb → 1° (muscle spindles → DRG) → 2° (Posterior thoracic nucleus → Dorsal/posterior spinocerebellar tract → ICP → 小腦蚓部)
- 上肢 → 1° (muscle spindles → DRG) → 2° (Accessory cuneate nucleus → Cuneocerebellar tract → ICP → Anterior lobe of cerebellum)
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| 反射弧 |
- lower limb → 1° (Golgi tendon organ) → 2° (Ventral/anterior spinocerebellar tract→ SCP → 蚓部)
- upper limb → 1° (Golgi tendon organ) → 2° (Rostral spinocerebellar tract → ICP → 小脑)
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