氟曲马唑
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臨床資料 | |
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AHFS/Drugs.com | 国际药品名称 |
ATC碼 | |
识别信息 | |
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CAS号 | 119006-77-8 ![]() |
PubChem CID | |
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KEGG | |
ChEBI | |
ChEMBL | |
CompTox Dashboard (EPA) | |
ECHA InfoCard | 100.170.770 |
化学信息 | |
化学式 | C22H16F2N2 |
摩尔质量 | 346.38 g·mol−1 |
3D模型(JSmol) | |
手性 | 外消旋混合物 |
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氟曲马唑(英語:Flutrimazole)是一种广谱抗真菌药,用于皮肤真菌病的局部治疗。氟曲马唑是一种咪唑衍生物,其抗真菌活性已在体外、体内得到证实,和克霉唑相近,比联苯苄唑要高。[1]
作用机理
[编辑]氟曲马唑通过抑制真菌羊毛甾醇14α-脱甲基酶的活性,影响麦角固醇的合成。
参见
[编辑]参考资料
[编辑]The Merck Index, 12th Edition. 4247
- ^ Alomar A, Videla S, Delgadillo J, Gich I, Izquierdo I, Forn J. Flutrimazole 1% dermal cream in the treatment of dermatomycoses: a multicentre, double-blind, randomized, comparative clinical trial with bifonazole 1% cream. Efficacy of flutrimazole 1% dermal cream in dermatomycoses. Catalan Flutrimazole Study Group. Dermatology. 1995, 190 (4): 295–300. PMID 7655109. doi:10.1159/000246720.
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