氟曲马唑
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| 臨床資料 | |
|---|---|
| AHFS/Drugs.com | 国际药品名称 |
| ATC碼 | |
| 识别信息 | |
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| CAS号 | 119006-77-8  |
| PubChem CID | |
| ChemSpider | |
| UNII | |
| KEGG | |
| ChEBI | |
| ChEMBL | |
| CompTox Dashboard (EPA) | |
| ECHA InfoCard | 100.170.770 |
| 化学信息 | |
| 化学式 | C22H16F2N2 |
| 摩尔质量 | 346.38 g·mol−1 |
| 3D模型（JSmol） | |
| 手性 | 外消旋混合物 |
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氟曲马唑（英語：Flutrimazole）是一种广谱抗真菌药，用于皮肤真菌病的局部治疗。氟曲马唑是一种咪唑衍生物，其抗真菌活性已在体外、体内得到证实，和克霉唑相近，比联苯苄唑要高。[1]
作用机理
[编辑]氟曲马唑通过抑制真菌羊毛甾醇14α-脱甲基酶的活性，影响麦角固醇的合成。
参见
[编辑]参考资料
[编辑]The Merck Index, 12th Edition. 4247
- ^ Alomar A, Videla S, Delgadillo J, Gich I, Izquierdo I, Forn J. Flutrimazole 1% dermal cream in the treatment of dermatomycoses: a multicentre, double-blind, randomized, comparative clinical trial with bifonazole 1% cream. Efficacy of flutrimazole 1% dermal cream in dermatomycoses. Catalan Flutrimazole Study Group. Dermatology. 1995, 190 (4): 295–300. PMID 7655109. doi:10.1159/000246720.
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