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飘带图

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肌红蛋白结合血基质与氧气(红色圆球)的飘带图 (PDB 1MBO)

飘带图(ribbon diagram),又被称作理查森图(Richardson diagram),用来表示蛋白质构造的三维模型。 用3D形式的彩带显示蛋白质主链的整体路径和架构,并作为可视框架, 在其上镶嵌原子结构的细节, 例如右图中结合活性肌红蛋白与氧原子球飘带图。 在这种图中其中α螺旋被画成盘绕的带或粗管,β折叠显示为箭头, 而线或细管显示为非重复的线圈或环。 多肽链的方向由箭头局部显示, 一些不同的多肽骨架可以通过彩条带的颜色变化表示。

历史

现在一般相信第一个有系统性的画出飘带图的是珍·S·理察森,她在1980年以手画出第一张飘带图的磷酸丙糖异构酶,并发表在期刊 Advances in Protein Chemistry, 不过她的绘图有受到一些之前蛋白质的绘图的影响。

理查森手绘的磷酸丙糖异构酶飘带图 (PDB 1TIM)

软件与数据库

现在有一些软件如 Molscript 和 PyMol 可以协助建立蛋白质的飘带图。

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飘带图
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