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重大创伤

重大创伤
医护人员照顾担架床上一位头部遭受枪伤的患者,已给予气管插管,背景可见使用呼吸器。
医护人员照顾担架床上一位头部遭受枪伤的患者,已给予气管插管,背景可见使用呼吸器
分类和外部资源
医学专科急诊医学创伤外科英语Trauma surgery
ICD-10S00、​S90、​T14.0
[编辑此条目的维基数据]

重大chuāng(英语:Major trauma)是指任何可能导致长期失能死亡创伤[1]。造成重大创伤的原因很多,包含钝性创伤穿透性创伤,例如跌倒车祸刺伤枪伤

2002年,意外事故和故意伤害是全球第五和第七大死因,分别占所有死亡人数的6.23%和2.84%。基于研究目的,重大创伤定义为外伤严重度分数英语Injury Severity Score[2][3]大于15[4]

分类

创伤通常按严重程度、伤害的位置、或综合两者来进行分类[5]。创伤也可以按人口统计学分类,例如年龄或性别[6]。也可以根据伤害对身体施力的类型进行分类,例如钝性创伤或穿透性创伤。出于研究目的,可以使用基于国际疾病与相关健康问题统计分类(ICD-9-CM)的巴雷尔氏诊断统计矩阵(Barel matrix)对创伤进行分类,用于将创伤分类国际标准化英语International standard[7]。重大创伤有时按身体部位分类,其中40%是多重创伤,30%头部损伤,20%胸部创伤,10%腹部创伤,2%肢体创伤[6][8]

有多种量表可量化评估损伤的严重程度,用于对病患进行分类或统计分析。简易外伤分数英语Abbreviated Injury Scale[9]格拉斯哥昏迷指数常用于量化损伤程度以进行分类,并可让医疗系统在临床环境中监视或预测病患的病情趋势[10]。数据也可用于流行病学调查和研究[11]

严重创伤的病患中约有2%患有脊髓损伤[12]

病因

任何作用于身体的物理性外力都可能造成损伤[13]。创伤致死的主要原因是钝性创伤、车祸、跌倒,其次是刺伤等穿透性创伤[14][15]

作为统计用途,伤害分为故意伤害(例如自杀)或意外事故(例如车祸)。故意伤害是造成创伤的常见原因[16]。子弹或刀等异物英语Foreign body进入人体组织可造成开放性伤口,属于穿透性创伤。在美国,大多数由穿透性创伤造成的死亡发生在都会区,其中80%是由枪支造成的[17]爆炸伤英语Blast injury是造成创伤的复合性病因,因为它通常既包括钝性创伤也包括穿透性创伤,还可能伴有灼伤。创伤也可能与特定活动有关,例如职业伤害运动伤害[18]

诊断

遭散弹枪近距离爆炸伤的膝部X光照片,在粉碎的髌骨、远端股骨、近端胫骨的内部及周围可见许多子弹小球。
散弹枪近距离爆炸伤英语Blast injury膝部X光照片,在粉碎的髌骨、远端股骨、近端胫骨的内部及周围可见许多子弹小球。

理学检查

第一阶段理学检查要确认任何危及生命的问题,可能在运送病患的过程中或到达医院时执行。第二阶段理学检查包括对腹部骨盆胸部区域的系统评估、完整检视身体表面以发现所有损伤、以及神经学检查英语Neurological examination。损伤的征象可能稍晚才会显现,或损伤可能在初步评估中遗漏,例如病患初进医院急诊室[19]。通常理学检查是有系统地进行,首先检查是否存在任何即时生命威胁(初步调查),然后进行更深入的检查(二次调查)[20]

影像检查

全身X光检查发现双侧股骨骨折,属于重大创伤。

重大创伤病患通常会接受胸部和骨盆的X光检查[8],并根据损伤的机转和表现使用外伤重点式超声波评估英语Focused assessment with sonography for traumaFAST)检查是否有内部出血英语Internal bleeding。对于血压心率相对稳定且血氧浓度较高的病患,计算机断层成像很有用[8][21]全身计算机断层成像英语Full-body CT scan可以提高重大创伤病患的存活率[22][23]。这些扫描使用静脉注射的造影剂,而非口服的[24]。有专家担心在创伤不明的状况下,未先确认肾功能是否足够就给予静脉造影剂,也许会损害肾脏,但相关证据并未发现显著损害[21]

美国急诊室有15%的创伤病患接受计算机断层成像或核磁共振检查[25]低血压或心率加快且怀疑腹部出血时,建议跳过计算机断层成像而直接进行手术[26]。现代的64切计算机断层成像可以高度准确地排除钝性创伤是否造成重要的颈部损伤[27]

处置

美国海军搜索与救援演习,医护兵英语Hospital corpsman确认气管插管创伤病患的导管位置。
典型的创伤治疗室。

到院前

在送达最近能够医治创伤的医院前,利用稳定技巧英语Stabilization (medicine)可以提高病患在这段路程的存活机会。紧急医疗服务决定哪些病患需要在创伤中心接受治疗,并检查与处理呼吸道、呼吸、循环英语ABC (medicine)、评估失能、检查其他伤害,以提供病患初步的稳定[19]

到院前以颈圈英语Cervical collar固定颈部并将病患放在长背板英语Spinal board上做脊椎固定英语Spinal immobilization非常重要,但是由于缺乏支持的证据,这种做法不受欢迎;相对的,如果满足更多特定条件,比如年龄或神经功能缺损英语Neurological deficit,则建议必须使用这些辅助工具[28][29]。移动病患前可以利用其他医疗运输设备来帮忙,例如长躯干固定器英语Kendrick Extrication Device[30][31]。重要的是在伤口上直接加压以迅速控制严重的出血,如果症状持续,可以考虑使用止血剂英语Antihemorrhagic止血带[32]。其他状况包括急性呼吸道阻塞英语Airway obstruction、恶化的颈部血肿意识不清需要气管插管等,然而目前尚不确定这些情况是在到达医院前或在医院中进行何者为佳[33]

快速运送重伤病患可改善创伤的预后[8][19]。与地面运输相比,直升机运输可降低成年创伤病患的死亡率[34]。在到达医院之前,与基本救命术英语Basic life support相比,提供进阶生命救命术英语Advanced life support并不能大幅改善重大创伤的结果[35][36]。到院前是否应给予静脉输液治疗的相关证据尚无定论,但有些证据表示这可能有害[37]。与没有创伤中心的医院相比,有创伤中心者治疗结果较佳[8];创伤病患能直接送到创伤治疗中心者,治疗结果可能较佳[38]

到院后

创伤病患的治疗通常需要许多医疗专业人员的协助,包括医生护士呼吸治疗师社会工作者。通常先进行初步调查,评估病患的呼吸道、呼吸、循环、神经系统的状况[39]。这些步骤可能同时进行,也可能取决于其紧迫性,例如张力性气胸或大动脉出血。初步调查通常包括对颈椎的评估,尽管要等到影像检查或病情改善后才能确定排除颈椎的问题。直接威胁生命的问题获得控制后,病患可能被送进手术室立即以外科手术处理伤势,或者进行二次调查,更详细地从头到脚全面评估[40]

气管插管的适应症包括呼吸道阻塞、无法保护呼吸道、呼吸衰竭[41],这些适应症的例子包括颈部穿透性创伤、正在恶化的颈部血肿、失去知觉等。创伤的复苏包括控制住活动性出血,检查生命征象、执行心电图、建立血管通路英语Vascular access。应进行其他测试以取得当前血液化学数据,例如动脉血气体分析英语Arterial blood gas test血栓弹力图英语Thromboelastography[42][43]。一般认为心肺复苏术对因创伤而心搏停止的病患效果不佳,但仍建议给予[44],处理潜在病因可能会有帮助,比如气胸心包填塞[44]

某些创伤让训练有素的医疗人员来维持呼吸道、呼吸、循环功能可能是有益的,例如颌面创伤[45]

药物

传明酸可减少因创伤而持续流血者的死亡率,对轻度到中度脑外伤及计算机断层成像显示有颅内出血的病患也有帮助[46][47][48],但是似乎只有在创伤后的前三个小时内使用才有益[49]。对于严重的出血,例如凝血病,可能适合给予重组因子VIIa英语Recombinant factor VIIa(一种有助于凝血的蛋白质[8][50],但似乎未能降低死亡率[51],不建议用于没有重组因子VII缺乏症病史的病患,除非是人体试验[52]

有些药物可以与其他治疗处置合并给予,以稳定遭受严重损害的病患[6]。虽然强心剂英语Inotrope(如去甲基肾上腺素)有时会用于创伤导致的出血性休克,但仍缺乏支持的证据[53],因此截至2012年仍未列入建议[54]。在某些情况下,适度的低血压是被允许的[55]

外科手术

是否进行手术取决于损伤的程度和解剖位置。必须先能控制住出血,然后才能有妥善的修复[56]损伤控制手术英语Damage control surgery[57]用于处理严重的创伤,如果未能妥善处理,可能因代谢性酸中毒英语Metabolic acidosis失温症低血压等一系列过程导致死亡[8],手术的主要原则是采用最少的步骤来挽救生命和肢体,将比较次要的步骤留待病患状况更稳定后再执行[8]。所有创伤病患中约15%有腹部损伤,其中约25%需要进行探查性手术英语Exploratory surgery。可预防的创伤致死大多数起因于未能发现腹腔内出血[58]

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  50. ^ Roppolo LP, Wigginton JG, Pepe PE. Intravenous fluid resuscitation for the trauma patient. Curr Opin Crit Care. 2010, 16 (4): 283–88. PMID 20601865. doi:10.1097/MCC.0b013e32833bf774. 
  51. ^ Hauser CJ, Boffard K, Dutton R, et al. Results of the CONTROL trial: efficacy and safety of recombinant activated Factor VII in the management of refractory traumatic hemorrhage. J Trauma. September 2010, 69 (3): 489–500. PMID 20838118. doi:10.1097/TA.0b013e3181edf36e. 
  52. ^ Simpson, E; Lin, Y; Stanworth, S; Birchall, J; Doree, C; Hyde, C. Recombinant factor VIIa for the prevention and treatment of bleeding in patients without haemophilia. Cochrane Database of Systematic Reviews. Mar 14, 2012, 3 (3): CD005011. PMID 22419303. doi:10.1002/14651858.CD005011.pub4. hdl:10871/13808. 
  53. ^ Senz, A; Nunnink, L. Review article: inotrope and vasopressor use in the emergency department. Emergency Medicine Australasia. Oct 2009, 21 (5): 342–51. PMID 19694785. doi:10.1111/j.1742-6723.2009.01210.x. 
  54. ^ Kobayashi, L; Costantini, TW; Coimbra, R. Hypovolemic shock resuscitation. The Surgical Clinics of North America. Dec 2012, 92 (6): 1403–23. PMID 23153876. doi:10.1016/j.suc.2012.08.006. 
  55. ^ Vasopressor and Inotrope Usage in Shock (PDF). Department of Surgical Education, Orlando Regional Medical Center. Apr 19, 2011 [4 May 2014]. (原始内容存档 (PDF)于2021-01-27). 
  56. ^ Andrew B., MD Peitzman; Andrew B. Peitzman; Michael, MD Sabom; Donald M., MD Yearly; Timothy C., MD Fabian. The trauma manual. Hagerstwon, MD: Lippincott Williams & Wilkins. 2002. ISBN 978-0781726412. 
  57. ^ 嚴重外傷病人的初始照護. 台湾急诊医学会. [2020-09-25]. 
  58. ^ Fitzgerald, J.E.F.; Larvin, Mike. Chapter 15: Management of Abdominal Trauma. Baker, Qassim; Aldoori, Munther (编). Clinical Surgery: A Practical Guide. CRC Press. 2009: 192–204. ISBN 978-1444109627. 

参考书目

  • Jeff Garner; Greaves, Ian; Ryan, James R.; Porter, Keith R. Trauma Care Manual. London, England: Hodder Arnold. 2009. ISBN 978-0340928264. 
  • Feliciano, David V.; Mattox, Kenneth L.; Moore, Ernest J. Trauma, Seventh Edition (Trauma (Moore)). McGraw-Hill Professional. 2012. ISBN 978-0071663519. 
  • Andrew B., Peitzman; Michael, MD Sabom; Donald M., MD Yearly; Timothy C., MD Fabian. The trauma manual. Hagerstwon, MD: Lippincott Williams & Wilkins. 2002. ISBN 978-0781726412. 

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