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诺勃酮 临床资料 ATC码 识别信息
13-ethyl-17-hydroxy-18,19-dinorpregn-4-en-3-one
CAS号 1235-15-0 Y PubChem CID ChemSpider UNII CompTox Dashboard (EPA ) 化学信息 化学式 C 21 H 32 O 2 摩尔质量 316.47758 g/mol 3D模型(JSmol )
O=C4\C=C3/[C@@H]([C@H]2CC[C@]1([C@@H](CC[C@@]1(O)CC)[C@@H]2CC3)CC)CC4
InChI=1S/C21H32O2/c1-3-20-11-9-17-16-8-6-15(22)13-14(16)5-7-18(17)19(20)10-12-21(20,23)4-2/h13,16-19,23H,3-12H2,1-2H3/t16-,17+,18+,19-,20-,21-/m0/s1
Y Key:FTBJKONNNSKOLX-XUDSTZEESA-N
Y
诺勃酮 (乙基羟基二降孕烯酮 ) 是一种合成代谢类固醇 。最早由惠氏 实验室于1966年合成,作为增加体重和治疗身材矮小的药物进行试验,因为担心潜在的毒性没有进行商业销售。[1] 21世纪初在体育比赛运动员尿检中检出。[2]
^ Lee, Henry K. Inventor of 'clear' steroid gets 3 months in prison . The San Francisco Chronicle. 2006-08-04.
^ Catlin DH, Ahrens BD, Kucherova Y. Detection of norbolethone, an anabolic steroid never marketed, in athletes' urine. Rapid Communications in Mass Spectrometry . 2002;16(13):1273-5.
雄甾烷 (19碳)
肾上腺甾酮
雄异恶唑
勃拉睾酮 (Myagen)
勃拉嗪
1,4-雄烯二酮
宝丹酮十一烯酸酯 (Equipoise)
4-氯去氢甲基睾酮(Turinabol)
4-羟基-睾酮
卡普睾酮
氯司替勃
达那唑
脱氧甲基睾酮(Madol)
DHT
屈他雄酮(Masteron)
依奈替勃
环硫雄醇
氟甲睾酮(Halotestin)
甲酰勃龙
呋咱甲氢龙(Miotolan)
羟雄唑
美勃拉嗪
麦酒宝龙
美雄诺龙
美睾酮(Proviron)
美雄醇
美雄酮(Dianabol)
美替诺龙
美替诺龙庚酸酯(Primobolan)
甲基屈他雄酮(Superdrol)
甲睾酮
氧雄龙 (Anavar)
康复龙(Anadrol)
羟甲睾酮
普罗斯它诺唑
奎勃龙(Anabolicum Vister)
罗昔勃龙
硅雄酮
司坦唑醇 (Strombafort
康力龙 )
司腾勃龙
睾丸酮 `s (Sustamed
Sustanon)
1-睾丸素
硫甲睾酮
曲托龙
雌素酮(缺19碳)
勃来诺
乙基双烯醇酮
乙雌烯醇
米勃龙(Cheque Drops)
甲基去甲睾酮
美曲勃龙(R1881)
诺龙 (Deca Durabolin)
诺勃酮 (Genabol)
去甲氯司替勃
诺乙雄龙
甲基诺龙
环戊丙羟勃龙
普罗雄醇
四氢孕三烯酮(The Clear)
群勃龙(Fina)
激素原
受体
酶 (抑制剂 )
22-ABC
3,3′-Dimethoxybenzidine
3-Methoxybenzidine
Aminoglutethimide
Cyanoketone
Danazol
Etomidate
Mitotane
Trilostane
3β-HSD (I, II)
17β-HSD (I-XIV)
22-Oxime
Alfatradiol
Azelaic acid
β-Sitosterol
Bexlosteride
Dutasteride
表睾酮
Epristeride
Finasteride
Izonsteride
L-39
Lapisteride
Polyunsaturated fatty acids (α-linolenic acid, linoleic acid, γ-linolenic acid, oleic acid)
Turosteride
Vitamin B6
锌
1,4,6-Androstatriene-3,17-dione
4-Androstene-3,6,17-trione
4-Cyclohexylaniline
4-Hydroxytestosterone
5α-DHNET
Abyssinone II
Aminoglutethimide
Anastrozole
抗坏血酸 (维生素C )
Atamestane
Bifonazole
CGP-45,688
CGS-47,645
Clotrimazole
双氢睾酮
Difeconazole
Econazole
Exemestane
Fadrozole
Fenarimol
Finrozole
Formestane
Imazalil
Isoconazole
Ketoconazole
Letrozole
Liarozole
MEN-11066
Miconazole
Minamestane
Nimorazole
NKS01
ORG-33,201
Penconazole
Plomestane
Prochloraz
Propioconazole
Pyridoglutethimide
Rogletimide
Rotenone
Talarozole
Testolactone
Tioconazole
Triadimefon
Triadimenol
Troglitazone
Vorozole
YM511
锌
Note: 21-Hydroxylase inhibitors may also affect androgen levels as they prevent metabolism of androgen steroid precursors.
其他
间接
Estrogens/Antiestrogens (see here)
GnRH agonists/antagonists (see here )
Gonadotropins/Antigonadotropins (see here )
Plasma protein s (SHBG, ABP, Albumin)
Progestogens/Antiprogestins (see here )
Prolactin
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