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佩罗尼氏病

佩罗尼氏病
佩罗尼氏病患者
症状勃起功能障碍
类型阴茎疾病[*]纤维瘤疾病
风险因素吸烟
分类和外部资源
医学专科泌尿外科
ICD-11GB06.2
ICD-9-CM607.85
OMIM171000、​171000
DiseasesDB29308
MedlinePlus001278
eMedicine1061264
[编辑此条目的维基数据]

佩罗尼氏病,或称纤维性海绵体炎,是一种涉及阴茎纤维斑块生长的结缔组织病[1][2]。大约5%的男性患有这种病[3]。当罹患佩罗尼氏病时,瘢痕组织在阴茎海绵体外的白膜中形成,将导致阴茎弯曲、疼痛等诸多问题。患者以白种人居多,年龄多半在四十岁以上,也有患者十八岁就得到这种疾病[4][5][6][7]。虽然现在已有许多针对疗法,手术切除块状物是最佳方案。

病因

造成佩罗尼氏病的根本原因并不为人所知,但是性交时的阴茎外伤通常是佩罗尼氏病的直接原因,而这种创伤连患者本人可能也没有意识到[8]

新进研究发现[9]此种病患与正常男性相比下日后有高达43%几率罹患胃癌,39%更容易罹患睾丸癌和18%的可能性得到皮肤癌。但两者是否有内在联系尚在研究中,也有可能是易得某些癌症的体质同时也易得佩罗尼氏病。

治疗

根据97名佩罗尼氏病患者的研究,即使不经过治疗,12–13%的患者可能会自愈。但是40–50%的患者病情都会加重[10]。研究发现,有一种称为“Xiaflex”的药物也许可以治疗佩罗尼氏病。过去这种药物多用来治疗爪形手,此外手术切除瘢痕组织是最有效方式。

参考文献

  1. ^ Freedberg, Irwin M.; Fitzpatrick, Thomas B. Fitzpatrick's dermatology in general medicine 6th. New York: McGraw-Hill, Medical Pub. Division. 2003: 990. ISBN 0-07-138076-0. 
  2. ^ Levine, Laurence A.; Estrada, Carlos R.; Storm, Douglas W.; Matkov, Thomas G. Peyronie disease in younger men: characteristics and treatment results. Journal of Andrology. 2003-01, 24 (1) [2022-10-25]. ISSN 0196-3635. PMID 12514077. (原始内容存档于2022-10-25). 
  3. ^ Pollack, Andrew. Treatment for Penis Curvature Sees Results. The New York Times. 2012-06-04 [2022-10-25]. ISSN 0362-4331. (原始内容存档于2022-12-06) (美国英语). 
  4. ^ Levine, LaurenceA. Peyronie′s disease and erectile dysfunction: Current understanding and future direction. Indian Journal of Urology. 2006, 22 (3) [2023-02-20]. ISSN 0970-1591. doi:10.4103/0970-1591.27633. (原始内容存档于2022-10-25) (英语). 
  5. ^ Peyronie's disease - Who Named It?
  6. ^ Peyronie's Disease. [2007-12-03]. (原始内容存档于2007-10-20). 
  7. ^ Peyronie's disease - MayoClinic.com. [2007-12-03]. (原始内容存档于2013-05-22). 
  8. ^ Peyronie's disease: Causes. MayoClinic.com. [2010-03-18]. (原始内容存档于2013-06-06). 
  9. ^ 男生注意!陰莖這形狀 有43%機率得癌症. 中时新闻网. 2017-11-23 [2022-10-25]. (原始内容存档于2022-10-25) (中文(台湾)). 
  10. ^ Gelbard, M. K.; Dorey, F.; James, K. The natural history of Peyronie's disease. The Journal of Urology. 1990-12, 144 (6) [2022-10-25]. ISSN 0022-5347. PMID 2231932. doi:10.1016/s0022-5347(17)39746-x. (原始内容存档于2022-12-26). 

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佩罗尼氏病
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