三苄糖苷
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| 临床资料 | |
|---|---|
| 商品名 | Glyvenol |
| 其他名称 | 三苄葡甙 |
| AHFS/Drugs.com | 国际药品名称 |
| ATC码 | |
| 识别信息 | |
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| CAS号 | 10310-32-4  |
| PubChem CID | |
| ChemSpider | |
| UNII | |
| ChEMBL | |
| CompTox Dashboard (EPA) | |
| ECHA InfoCard | 100.030.612 |
| 化学信息 | |
| 化学式 | C29H34O6 |
| 摩尔质量 | 478.59 g·mol−1 |
| 3D模型（JSmol） | |
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三苄糖苷 (INN：tribenoside，TBS)，旧称三苄葡甙，是由两种光学异构体（α体和β体）组成的混合物，为一种毛细血管保护剂，具有抗炎、抗毒素、治愈创伤组织及较弱的镇痛作用[1][2]，与神经鞘氨醇合用可有效预防革兰阴性及阳性菌的感染。由加拿大Ciba-Geigy于20世纪50年代开发[3]。现常用于治疗痔疮[4]。
已证明三苄糖苷会诱发与人巨细胞病毒再激活相关的药物超敏反应综合征反应[5]
参考文献
[编辑]- ^ Jaques R. The pharmacological activity of tribenoside.. Pharmacology. 1977, 15 (5): 445–60. PMID 578928. doi:10.1159/000136721.
- ^ Kikkawa Y, Takaki S, Matsuda Y, Okabe K, Taniguchi M, Oomachi K, Samejima T, Katagiri F, Hozumi K, Nomizu M. The influence of Tribenoside on expression and deposition of epidermal laminins in HaCaT cells.. Biol Pharm Bull. 2010, 33 (2): 307–10. PMID 20118558. doi:10.1248/bpb.33.307
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- ^ 田兴，孙子含，陈阳，等. 三苄糖苷有关物质的研究. 中国药物化学杂志. 2023, 33 (11): 845–848. doi:10.14142/j.cnki.cn21-1313/r.2023.11.006.
- ^ Lorenc Z, Gökçe Ö. Tribenoside and lidocaine in the local treatment of hemorrhoids: an overview of clinical evidence.. Eur Rev Med Pharmacol Sci. 2016, 20 (12): 2742–51. PMID 27383331.
- ^ Hashizume H, Takigawa M. Drug-induced hypersensitivity syndrome associated with cytomegalovirus reactivation: immunological characterization of pathogenic T cells. Acta Derm. Venereol. 2005, 85 (1): 47–50. PMID 15848991. doi:10.1080/00015550410024094 .
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