Pegaspargaza
| Klinički podaci | |
|---|---|
| Drugs.com | Monografija |
| Način primene | Intramaskularno, intravenozno |
| Identifikatori | |
| CAS broj | 130167-69-0  |
| ATC kod | L01XX24 (WHO) |
| DrugBank | DB00059 |
| Hemijski podaci | |
| Molarna masa | 0,000 |
Pegaspargaza (Oncaspar) je modifikovani enzim, koji se koristi kao antineoplastični agens. On je forma L-asparaginaze na kojoj je izvršena pegilacija.[1][2][3]
Ovaj lek se koristi u tretmanu akutne limfocitne leukemije.[4][5]
Reference
[уреди | уреди извор]- ^ Graham ML: Pegaspargase: a review of clinical studies. Adv Drug Deliv Rev. 2003 Sep 26;55(10):1293-302. PMID 14499708
- ^ Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS (2011). „DrugBank 3.0: a comprehensive resource for omics research on drugs”. Nucleic Acids Res. 39 (Database issue): D1035—41. PMC 3013709
. PMID 21059682. doi:10.1093/nar/gkq1126.
- ^ David S. Wishart; Craig Knox; An Chi Guo; Dean Cheng; Savita Shrivastava; Dan Tzur; Bijaya Gautam; Murtaza Hassanali (2008). „DrugBank: a knowledgebase for drugs, drug actions and drug targets”. Nucleic acids research. 36 (Database issue): D901—6. PMC 2238889 . PMID 18048412. doi:10.1093/nar/gkm958.
- ^ Graham ML (2003). „Pegaspargase: a review of clinical studies”. Adv. Drug Deliv. Rev. 55 (10): 1293—302. PMID 14499708. doi:10.1016/S0169-409X(03)00110-8.
- ^ Patel SS, Benfield P (1996). „New drug profile: pegaspargase (Polyethylene Glycol L-Asparaginase)”. Clinical Immunotherapeutics. 5 (6): 492—496.
Literatura
[уреди | уреди извор]- Hardman JG, Limbird LE, Gilman AG (2001). Goodman & Gilman's The Pharmacological Basis of Therapeutics (10. изд.). New York: McGraw-Hill. ISBN 0071354697. doi:10.1036/0071422803.
- Thomas L. Lemke; David A. Williams, ур. (2007). Foye's Principles of Medicinal Chemistry (6. изд.). Baltimore: Lippincott Willams & Wilkins. ISBN 0781768799.
Spoljašnje veze
[уреди | уреди извор]
 | Molimo Vas, obratite pažnju na važno upozorenje u vezi sa temama iz oblasti medicine (zdravlja). |
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