Heksobarbital
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| IUPAC ime | |
|---|---|
5-(cikloheks-1-en-1-il)-1,5-dimetil-1,3-diazinan-2,4,6-trion | |
| Klinički podaci | |
| Prodajno ime | Barbidorm, Citopan, Cyclopal, Cyclopan |
| Drugs.com | Monografija |
| Način primene | Oralno |
| Identifikatori | |
| CAS broj | 56-29-1  |
| ATC kod | N05CA16 (WHO), N01AF02 |
| DrugBank | DB01355 |
| KEGG | C11723 |
| ChEMBL | CHEMBL5706 |
| Hemijski podaci | |
| Formula | C12H16N2O3 |
| Molarna masa | 236.267 |
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| Fizički podaci | |
| Tačka topljenja | 1.465 °C (2.669 °F) |
Heksobarbital je barbiturat koji je efektivan kao hipnotik i sedativ.[1][2][3][4][5][6]
Reference
[уреди | уреди извор]- ^ Takenoshita R, Toki S: [New aspects of hexobarbital metabolism: stereoselective metabolism, new metabolic pathway via GSH conjugation, and 3-hydroxyhexobarbital dehydrogenases] Yakugaku Zasshi. 2004 Dec;124(12):857-71. PMID 15577260
- ^ Wahlstrom G: A study of the duration of acute tolerance induced with hexobarbital in male rats. Pharmacol Biochem Behav. 1998 Apr;59(4):945-8. PMID 9586853
- ^ Korkmaz S, Ljungblad E, Wahlstrom G: Interaction between flumazenil and the anesthetic effects of hexobarbital in the rat. Brain Res. 1995 Apr 10;676(2):371-7. PMID 7614008
- ^ Dall V, Orntoft U, Schmidt A, Nordholm L: Interaction of the competitive AMPA receptor antagonist NBQX with hexobarbital. Pharmacol Biochem Behav. 1993 Sep;46(1):73-6. PMID 8255925
- ^ Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS (2011). „DrugBank 3.0: a comprehensive resource for omics research on drugs”. Nucleic Acids Res. 39 (Database issue): D1035—41. PMID 21059682.
- ^ Wishart DS, Knox C, Guo AC, Cheng D, Shrivastava S, Tzur D, Gautam B, Hassanali M (Nucleic Acids Res) (2008). „DrugBank: a knowledgebase for drugs, drug actions and drug targets”. 36 (Database issue): D901—6. PMID 18048412.
Spoljašnje veze
[уреди | уреди извор]| GABAA receptor |
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| Alfa-2-adrenergički receptor |
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| Melatoninski receptor |
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| Histaminski receptor & Acetilholinski receptor |
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| 5-HT2A & α1- adrenergički |
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| GABAB receptor / GHB receptor |
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| Oreksinski receptori |
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| Drugi receptori/ negrupisani |
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 | Molimo Vas, obratite pažnju na važno upozorenje u vezi sa temama iz oblasti medicine (zdravlja). |
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