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Keratin

Humant keratin 1
Identifikasjon
Symbol(er) KRT1
Entrez 3848
OMIM 139350
RefSeq NM_006121
UniProt P04264
Annen info
Kromosom 12q11-13
Mikroskopbilde av keratinfilamenter inne i celler.

Keratin er et fiberdannende protein, som er rikt på cystein. Stoffet utgjør hoveddelen av:

Keratinmolekyler er skrueformede og fiberaktige. De snor seg om hverandre og danner på den måten tråder, som kalles hornfilamenter. Disse proteinene inneholder en høy prosentandel av svovelholdige aminosyrer, som nevnt mest cystein, som danner disulfidbindinger mellom de enkelte molekyler. Det skaper en temmelig stiv, men likevel bøyelig struktur.

Når noe keratiniserer, blir det forhornet. Det gjelder f.eks. hudceller → overhud, hårsekker → hår, neglebånd → negler og horn → horn.

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Keratin
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