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Tasuku Honjo

Tasuku Honjo
本庶 佑
Kelahiran (1942-01-27) 27 Januari 1942 (umur 82)
PendidikanUniversiti Kyoto (BS, MD, PhD)
Terkenal keranaClass switch recombination
IL-4, IL-5, AID
Cancer immunotherapy
PD-1
AnugerahHadiah Impeial (1996)
Koch Prize (2012)
Order of Culture (2013)
Tang Prize (2014)
Kyoto Prize (2016)
Alpert Prize (2017)
Nobel Prize in Physiology or Medicine (2018)
Kerjaya saintifik
BidangImunologi Molekul
InstitusiUniversiti Kyoto
Penasihat kedoktoranYasutomi Nishizuka
Osamu Hayaishi
Pelajar terkemukaShizuo Akira

Tasuku Honjo (本庶 佑, Honjo Tasuku) (lahir 27 Januari 1942) adalah seorang pakar imunologi Jepun , dan pemenang Nobel yang terbaik yang dikenali kerana pengenalan Protein Maut Sel Diprogram (PD-1).[1] Beliau juga dikenali dengan atas usaha pengenalan molekular sitokin: IL-4 dan IL-5,[2] serta penemuan sitidina deaminase diaruh pengaktifan yang penting untuk rekombinasi pertukaran kelas dan hipermutasi somatik.[3]

Pada tahun 2018, beliau dianugerahi Hadiah Nobel dalam Fisiologi atau Perubatan bersama-sama dengan James P. Allison,[4] di mana kedua-duanya telah memenangi Hadiah Sains Farmaseutikal Tang untuk pencapaian yang sama pada tahun 2014.[5]

  1. ^ Ishida, Y.; Agata, Y.; Shibahara, K.; Honjo, T. (1992). "Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death". The EMBO Journal. Wiley. 11 (11): 3887–3895. doi:10.1002/j.1460-2075.1992.tb05481.x. ISSN 0261-4189. PMC 556898. PMID 1396582.
  2. ^ Kumanogoh, Atsushi; Ogata, Masato (2010-03-25). "The study of cytokines by Japanese researchers: a historical perspective". International Immunology. 22 (5): 341–345. doi:10.1093/intimm/dxq022. ISSN 0953-8178. PMID 20338911. Dicapai pada 2018-10-01.
  3. ^ Robert Koch Foundation confers award on Professors Honjo and Wimmer
  4. ^ Hannah, Devlin. "James P Allison and Tasuku Honjo win Nobel prize for medicine". The Guardian. Dicapai pada 1 October 2018.
  5. ^ "2014 Tang Prize in Biopharmaceutical Science". Diarkibkan daripada yang asal pada 20 Oktober 2017. Dicapai pada 2016-06-18. Unknown parameter |dead-url= ignored (bantuan)

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Tasuku Honjo
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