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ഹൈഡ്രോക്സി കാർബാമൈഡ് .
അരിവാൾ കോശ വിളർച്ച , ക്രോണിക് മൈലോജീനസ് ലുക്കീമിയ, ഗർഭാശയ ക്യാൻസർ, പോളിസിത്തീമിയ വെറ എന്നിവയ്ക്കതിരെ ഉപയോഗിക്കുന്ന ഒരു മരുന്നാണ് 'ഹൈഡ്രോക്സി യൂറിയ എന്നും അറിയപ്പെടുന്ന ഹൈഡ്രോക്സി കാർബാമൈഡ്. [ 2] [ 3] സിക്കിൾ സെൽ ഡിസീസിൽ ഹീമോഗ്ലോബിൻ വർദ്ധിപ്പിക്കുകയും സെൽ ആക്രമണങ്ങളുടെ എണ്ണം കുറയ്ക്കുകയും ചെയ്യുന്നു.
Antiviral drugs: antiretroviral drugs used against
HIV (primarily J05)
Entry/fusion inhibitors (Discovery and development)
gp41 (Enfuvirtide (ENF, T-20))
CCR5 (Maraviroc (MVC)
Vicriviroc† , Cenicriviroc† , PRO 140† )
CD4 (Ibalizumab† )
gp120 (Fostemsavir† )
Reverse-transcriptase inhibitors (RTIs)
Nucleoside and nucleotide (NRTI)
Nucleoside analogues/NRTIs: Abacavir (ABC)°#
Didanosine (ddI)
Emtricitabine (FTC)°
Lamivudine (3TC)°#
Stavudine (d4T)#
Zidovudine (AZT, ZDV)#
Amdoxovir†
Apricitabine†
Censavudine†
Elvucitabine†
Racivir†
Stampidine†
4′-Ethynyl-2-fluoro-2′-deoxyadenosine(EFdA)§
Zalcitabine (ddC)◊
Nucleotide analogues/NtRTIs: Tenofovir disoproxil (TDF)°#
Tenofovir alafenamide (TAF)
Non-nucleoside (NNRTI)(Discovery and development)
1st generation
Efavirenz (EFV)°#
Nevirapine (NVP)#
Delavirdine (DLV)◊
2nd generation
diarylpyrimidines
Etravirine (ETR)
Rilpivirine (RPV)°
Doravirine°
Integrase inhibitors (Integrase strand transfer inhibitors (INSTI))
Dolutegravir (DTG)°
Elvitegravir (EVG)°
Raltegravir (RAL)°
BI 224436†
Cabotegravir†
Bictegravir (BIC)†
MK-2048†
Maturation inhibitors Protease Inhibitors (PI)(Discovery and development)
1st generation
Amprenavir (APV)◊
Fosamprenavir (FPV)
Indinavir (IDV)◊
Lopinavir (LPV)
Nelfinavir (NFV)
Ritonavir (RTV)#
Saquinavir (SQV)#
2nd generation
Atazanavir (ATV)°#
Darunavir (DRV)°#
Tipranavir (TPV)
Combined formulations
Abacavir/lamivudine°#
Abacavir/dolutegravir/lamivudine°
Abacavir/lamivudine/zidovudine
Atazanavir/cobicistat
Bictegravir/emtricitabine/tenofovir alafenamide
Darunavir/cobicistat
Doravirine/lamivudine/tenofovir disoproxil
Efavirenz/emtricitabine/tenofovir°#
Elvitegravir/cobicistat/emtricitabine/tenofovir alafenamide
Elvitegravir/cobicistat/emtricitabine/tenofovir°
Emtricitabine/tenofovir alafenamide
Emtricitabine/rilpivirine/tenofovir alafenamide
Emtricitabine/rilpivirine/tenofovir°
Emtricitabine/tenofovir°#
Lamivudine/raltegravir
Lamivudine/zidovudine#
Lopinavir/ritonavir°#
Pharmacokinetic boosters
Cobicistat (c)
Ritonavir (r)#
Experimental agents
Uncoating inhibitors Transcription inhibitors Translation inhibitors Other
Abzyme
BIT225†
Calanolide A
Ceragenin
Cyanovirin-N
Diarylpyrimidines
Epigallocatechin gallate (EGCG)
Foscarnet
Fosdevirine†
Griffithsin
Hydroxycarbamide
KP-1461†
Miltefosine
Portmanteau inhibitors
Scytovirin
Seliciclib†
Synergistic enhancers
Tre recombinase
Zinc finger protein transcription factor
Failed agents
Aplaviroc
Atevirdine
Brecanavir
Capravirine
Dexelvucitabine
Droxinavir
Lasinavir
Emivirine
Lersivirine
Lodenosine
Loviride
Mozenavir
Palinavir
Telinavir
# WHO-EM
‡ Withdrawn from market
Clinical trials:
† Phase III
§ Never to phase III
°DHHS
recommended initial regimen options.
◊ Formerly or rarely used agent.
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