Singles
2010 Atlanta Tennis Championships
Final
Champion	Mardy Fish
Runner-up	John Isner
Score	4–6, 6–4, 7–6(7–4)
Details
Draw	28 (4 Q / 3 WC )
Seeds	8
Events
Singles Doubles
← 2009 · Atlanta Tennis Championships · 2011 →

Robby Ginepri was the defending champion, but lost in the second round to fellow American and eventual champion Mardy Fish. Fish won his second title of 2010 and in July by defeating compatriot John Isner 4–6, 6–4, 7–6^(7–4).

The top four seeds receive a bye into the second round.

	Semifinals							Final
	1/WC	Andy Roddick	65	3
	6	Mardy Fish	77	6
								6	Mardy Fish	4	6	77
								2	John Isner	6	4	64
		Kevin Anderson	3	79	3
	2	John Isner	6	67	6

	First round							Second round							Quarterfinals							Semifinals
								1/WC	A Roddick	6	61	6
		R Ram	6	77					R Ram	1	77	3
		K Beck	4	64											1/WC	A Roddick	4	6	6
		I Marchenko	6	77											7	X Malisse	6	3	4
		K Vliegen	4	64					I Marchenko	3	3
	Q	R Sweeting	61	3				7	X Malisse	6	6
	7	X Malisse	77	6																		1/WC	A Roddick	65	3
																						6	M Fish	77	6
								4	H Zeballos	6	2	0
		T Dent	6	3	6				T Dent	4	6	6
		J Blake	3	6	4											T Dent	3	0
		R Ginepri	77	6											6	M Fish	6	6
	Q	N Lindahl	64	2					R Ginepri	1	5
	WC	J Ward	1	2				6	M Fish	6	7
	6	M Fish	6	6

	First round							Second round							Quarterfinals							Semifinals
	5	J Tipsarević	3	5
		K Anderson	6	7					K Anderson	7	6
	WC	D Young	7	6				WC	D Young	5	3
		D Sela	5	0												K Anderson	6	6
		L Lacko	4	77	77											L Lacko	3	4
	Q	I Kunitsyn	6	64	64				L Lacko	6	6
								3	L Hewitt	4	2
																							K Anderson	3	79	3
	8	B Becker	3	3																		2	J Isner	6	67	6
		M Russell	6	6					M Russell	1	6	7
		T Gabashvili	1	4					R Schüttler	6	2	5
		R Schüttler	6	6												M Russell	1	2
		M Przysiężny	4	6	64										2	J Isner	6	6
	Q	G Müller	6	4	77			Q	G Müller	6	66	67
								2	J Isner	4	78	79

• Main draw
• Qualifying Singles draw