SYNPR

SYNPR
Identifikatori
Aliasi	SYNPR
Vanjski ID-jevi	MGI: 1919253 HomoloGene: 11407 GeneCards: SYNPR
Lokacija gena (čovjek)
Hrom.	Hromosom 3 (čovjek)
Kraj	63,616,924 bp
Lokacija gena (miš)
Hrom.	Hromosom 14 (miš)
Kraj	9,184,983 bp
Obrazac RNK ekspresije
	; ;
	Više referentnih podataka o ekspresiji
Ontologija gena
Molekularna funkcija	• GO:0001948, GO:0016582 vezivanje za proteine; • syntaxin-1 binding;
Ćelijska komponenta	• sinapsa; • membrana; • međućelijske veze; • GO:0016023 citoplazmatska vezikula; • integral component of synaptic vesicle membrane; • synaptic vesicle membrane; • neuron projection; • integral component of membrane; • Sinapsna vezikula;
Biološki proces	• GO:0015915 transport;
	Izvori:Amigo / QuickGO
Ortolozi
	132204
	72003
	ENSG00000163630
	ENSMUSG00000056296
	Q8TBG9
	Q8BGN8
	NM_001130003; NM_144642
	NM_001163032; NM_028052
	NP_001123475; NP_653243
	NP_001156504; NP_082328
	Wikipodaci
Pogledaj/uredi – čovjek	Pogledaj/uredi – miš

Sinaptoporin jest protein koji je kod ljudi kodiran genom SYNPR sa hromosoma 3.^[5]^[6]^[7]

Aminokiselinska sekvenca

Dužina polipeptidnog lanca je 265 aminokiselina, а molekulska težina 29.166 Da.^[8]

C: Cistein

D: Asparaginska kiselina

E: Glutaminska kiselina

F: Fenilalanin

G: Glicin

H: Histidin

I: Izoleucin

K: Lizin

L: Leucin

M: Metionin

N: Asparagin

P: Prolin

Q: Glutamin

R: Arginin

S: Serin

T: Treonin

V: Valin

W: Triptofan

Y: Tirozin

10	20	30	40	50
MCMVIFAPLF	AIFAFATCGG	YSGGLRLSVD	CVNKTESNLS	IDIAFAYPFR
LHQVTFEVPT	CEGKERQKLA	LIGDSSSSAE	FFVTVAVFAF	LYSLAATVVY
IFFQNKYREN	NRGPLIDFIV	TVVFSFLWLV	GSSAWAKGLS	DVKVATDPKE
VLLLMSACKQ	PSNKCMAIHS	PVMSSLNTSV	VFGFLNFILW	AGNIWFVFKE
TGWHSSGQRY	LSDPMEKHSS	SYNQGGYNQD	SYGSSSGYSQ	QASLGPTSDE
FGQQPTGPTS	FTNQI

Reference

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000163630 - Ensembl, maj 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000056296 - Ensembl, maj 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Leube RE (Aug 1994). "Expression of the synaptophysin gene family is not restricted to neuronal and neuroendocrine differentiation in rat and human". Differentiation. 56 (3): 163–71. doi:10.1046/j.1432-0436.1994.5630163.x. PMID 8034131.
^ Dai J, Ji C, Gu S, Wu Q, Wang L, Xu J, Zeng L, Ye X, Yin G, Xie Y, Mao Y (Sep 2003). "Cloning and sequence analysis of the human cDNA encoding the synaptoporin (delta), a highly conservative synaptic vesicle protein". Mol Biol Rep. 30 (3): 185–91. doi:10.1023/A:1024907723000. PMID 12974474. S2CID 40874195.
^ "Entrez Gene: SYNPR synaptoporin".
^ "UniProt, Q8TBG9" (jezik: engleski). Pristupljeno 6. 11. 2021.

Dopunska literatura

Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
Singec I, Knoth R, Ditter M, et al. (2002). "Synaptic vesicle protein synaptoporin is differently expressed by subpopulations of mouse hippocampal neurons". J. Comp. Neurol. 452 (2): 139–53. doi:10.1002/cne.10371. PMID 12271488. S2CID 30492933.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Tran MH, Yamada K, Nakajima A, et al. (2004). "Tyrosine nitration of a synaptic protein synaptophysin contributes to amyloid beta-peptide-induced cholinergic dysfunction". Mol. Psychiatry. 8 (4): 407–12. doi:10.1038/sj.mp.4001240. PMID 12740598.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.

Kategorije

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000163630 - Ensembl, maj 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000056296 - Ensembl, maj 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8034131-5] Leube RE (Aug 1994). "Expression of the synaptophysin gene family is not restricted to neuronal and neuroendocrine differentiation in rat and human". Differentiation. 56 (3): 163–71. doi:10.1046/j.1432-0436.1994.5630163.x. PMID 8034131.

[pmid12974474-6] Dai J, Ji C, Gu S, Wu Q, Wang L, Xu J, Zeng L, Ye X, Yin G, Xie Y, Mao Y (Sep 2003). "Cloning and sequence analysis of the human cDNA encoding the synaptoporin (delta), a highly conservative synaptic vesicle protein". Mol Biol Rep. 30 (3): 185–91. doi:10.1023/A:1024907723000. PMID 12974474. S2CID 40874195.

[entrez-7] "Entrez Gene: SYNPR synaptoporin".

[UniProt-8] "UniProt, Q8TBG9" (jezik: engleski). Pristupljeno 6. 11. 2021.

[1]

[2]

[3]

[4]

[5]

[6]

[7]

[8]

SYNPR

Aminokiselinska sekvenca

Reference

Dopunska literatura

Suggest as cover photo

Thank you for helping!

Install Wikiwand

Don't forget to rate us

Tell your friends about Wikiwand!

Enjoying Wikiwand?

Tell your friends and spread the love:

Your preferred languages

All languages

Follow Us

Don't forget to rate us

Our magic isn't perfect

Thank you for helping!

Oh no, there's been an error