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RNMTL1

RNMTL1
Identifikatori
AliasiMRM3
Vanjski ID-jeviOMIM: 612600 MGI: 1914640 HomoloGene: 10033 GeneCards: MRM3
Lokacija gena (čovjek)
Hromosom 17 (čovjek)
Hrom.Hromosom 17 (čovjek)[1]
Hromosom 17 (čovjek)
Genomska lokacija za RNMTL1
Genomska lokacija za RNMTL1
Bend17p13.3Početak782,353 bp[1]
Kraj792,509 bp[1]
Lokacija gena (miš)
Hromosom 11 (miš)
Hrom.Hromosom 11 (miš)[2]
Hromosom 11 (miš)
Genomska lokacija za RNMTL1
Genomska lokacija za RNMTL1
Bend11|11 B5Početak76,134,541 bp[2]
Kraj76,141,445 bp[2]
Obrazac RNK ekspresije
Više referentnih podataka o ekspresiji
Ontologija gena
Molekularna funkcija RNA methyltransferase activity
aktivnost sa transferazom
GO:0001948, GO:0016582 vezivanje za proteine
rRNA (guanosine-2'-O-)-methyltransferase activity
vezivanje sa RNK
GO:0102674, GO:0102675 methyltransferase activity
Ćelijska komponenta mitochondrial matrix
mitohondrija
Biološki proces rRNA processing
Metilacija
GO:0033168, GO:0036404, GO:1902360 RNA processing
rRNA 2'-O-methylation
Izvori:Amigo / QuickGO
Ortolozi
VrsteČovjekMiš
Entrez
Ensembl
UniProt
RefSeq (mRNK)

NM_018146
NM_001317947

NM_183263

RefSeq (bjelančevina)

NP_001304876
NP_060616

NP_899086

Lokacija (UCSC)Chr 17: 0.78 – 0.79 MbChr 11: 76.13 – 76.14 Mb
PubMed pretraga[3][4]
Wikipodaci
Pogledaj/uredi – čovjekPogledaj/uredi – miš

RNK metiltransferoliki protein 1 je enzim koji je kod ljudi kodiran genom RNMTL1.[5][6]

Dužina polipeptidnog lanca je 420 aminokiselina, a molekulska težina 47.020.[7]

Aminokiselinska sekvenca

Simboli
1020304050
MAALVRPARFVVRPLLQVVQAWDLDARRWVRALRRSPVKVVFPSGEVVEQ
KRAPGKQPRKAPSEASAQEQREKQPLEESASRAPSTWEESGLRYDKAYPG
DRRLSSVMTIVKSRPFREKQGKILLEGRRLISDALKAGAVPKMFFFSRLE
YLKELPVDKLKGVSLIKVKFEDIKDWSDLVTPQGIMGIFAKPDHVKMTYP
KTQLQHSLPLLLICDNLRDPGNLGTILRSAAGAGCSKVLLTKGCVDAWEP
KVLRAGMGAHFRMPIINNLEWETVPNYLPPDTRVYVADNCGLYAQAEMSN
KASDHGWVCDQRVMKFHKYEEEEDVETGASQDWLPHVEVQSYDSDWTEAP
AAVVIGGETYGVSLESLQLAESTGGKRLLIPVVPGVDSLNSAMAASILLF
EGKRQLRGRAEDLSRDRSYH

Reference

[uredi | uredi izvor]
  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000171861 - Ensembl, maj 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000038046 - Ensembl, maj 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Xu J, De Zhu J, Ni M, Wan F, Gu JR (Sep 2002). "The ATF/CREB site is the key element for transcription of the human RNA methyltransferase like 1(RNMTL1) gene, a newly discovered 17p13.3 gene". Cell Res. 12 (3–4): 177–97. doi:10.1038/sj.cr.7290124. PMID 12296377.
  6. ^ "Entrez Gene: RNMTL1 RNA methyltransferase like 1".
  7. ^ "UniProt, Q9HC36". Pristupljeno 12. 9. 2017.

Dopunska literatura

[uredi | uredi izvor]
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RNMTL1
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