ECD

ECD
Identifikatori
Aliasi	ECD
Vanjski ID-jevi	OMIM: 616464 MGI: 1917851 HomoloGene: 5256 GeneCards: ECD
Lokacija gena (čovjek)
Hrom.	Hromosom 10 (čovjek)
Kraj	73,169,055 bp
Lokacija gena (miš)
Hrom.	Hromosom 14 (miš)
Kraj	20,398,189 bp
Obrazac RNK ekspresije
	Više referentnih podataka o ekspresiji
Ontologija gena
Molekularna funkcija	• GO:0001105 transcription coactivator activity; • GO:0001948, GO:0016582 vezivanje za proteine; • histone acetyltransferase binding;
Ćelijska komponenta	• citoplazma; • jedro; • nukleoplazma; • R2TP complex; • citosol;
Biološki proces	• regulation of G1/S transition of mitotic cell cycle; • Ćelijska proliferacija; • GO:0009373 regulation of transcription, DNA-templated; • transcription by RNA polymerase II; • transcription, DNA-templated; • regulation of glycolytic process; • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II; • Prerada RNK; • mRNA processing;
	Izvori:Amigo / QuickGO
Ortolozi
	11319
	70601
	ENSG00000122882
	ENSMUSG00000021810
	O95905
	Q9CS74
	NM_001135752; NM_001135753; NM_007265
	NM_027475
	NP_001129224; NP_001129225; NP_009196
	NP_081751
	Wikipodaci
Pogledaj/uredi – čovjek	Pogledaj/uredi – miš

Protein SGT1 ie protein koji je kod ljudi kodoran genom ECD.^[5]^[6]^[7]

Aminokiselinska sekvenca

Dužina polipeptidnog lanca je 644 aminokiseline, а molekulska težina 72.758.^[8]

C: Cistein

D: Asparaginska kiselina

E: Glutaminska kiselina

F: Fenilalanin

G: Glicin

H: Histidin

I: Izoleucin

K: Lizin

L: Leucin

M: Metionin

N: Asparagin

P: Prolin

Q: Glutamin

R: Arginin

S: Serin

T: Treonin

V: Valin

W: Triptofan

Y: Tirozin

10	20	30	40	50
MEETMKLATM	EDTVEYCLFL	IPDESRDSDK	HKEILQKYIE	RIITRFAPML
VPYIWQNQPF	NLKYKPGKGG	VPAHMFGVTK	FGDNIEDEWF	IVYVIKQITK
EFPELVARIE	DNDGEFLLIE	AADFLPKWLD	PENSTNRVFF	CHGELCIIPA
PRKSGAESWL	PTTPPTIPQA	LNIITAHSEK	ILASESIRAA	VNRRIRGYPE
KIQASLHRAH	CFLPAGIVAV	LKQRPRLVAA	AVQAFYLRDP	IDLRACRVFK
TFLPETRIMT	SVTFTKCLYA	QLVQQRFVPD	RRSGYRLPPP	SDPQYRAHEL
GMKLAHGFEI	LCSKCSPHFS	DCKKSLVTAS	PLWASFLESL	KKNDYFKGLI
EGSAQYRERL	EMAENYFQLS	VDWPESSLAM	SPGEEILTLL	QTIPFDIEDL
KKEAANLPPE	DDDQWLDLSP	DQLDQLLQEA	VGKKESESVS	KEEKEQNYDL
TEVSESMKAF	ISKVSTHKGA	ELPREPSEAP	ITFDADSFLN	YFDKILGPRP
NESDSDDLDD	EDFECLDSDD	DLDFETHEPG	EEASLKGTLD	NLKSYMAQMD
QELAHTCISK	SFTTRNQVEP	VSQTTDNNSD	EEDSGTGESV	MAPVDVDLNL
VSNILESYSS	QAGLAGPASN	LLQSMGVQLP	DNTDHRPTSK	PTKN

Reference

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000122882 - Ensembl, maj 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000021810 - Ensembl, maj 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Sato T, Jigami Y, Suzuki T, Uemura H (Feb 1999). "A human gene, hSGT1, can substitute for GCR2, which encodes a general regulatory factor of glycolytic gene expression in Saccharomyces cerevisiae". Mol Gen Genet. 260 (6): 535–40. doi:10.1007/s004380050926. PMID 9928932. S2CID 28511451.
^ Gaziova I, Bonnette PC, Henrich VC, Jindra M (maj 2004). "Cell-autonomous roles of the ecdysoneless gene in Drosophila development and oogenesis". Development. 131 (11): 2715–25. doi:10.1242/dev.01143. PMID 15128659.
^ "Entrez Gene: ECD ecdysoneless homolog (Drosophila)".
^ "UniProt, O95905". Pristupljeno 1. 9. 2021.

Dopunska literatura

Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Bork JM, Peters LM, Riazuddin S, et al. (2001). "Usher Syndrome 1D and Nonsyndromic Autosomal Recessive Deafness DFNB12 Are Caused by Allelic Mutations of the Novel Cadherin-Like Gene CDH23". Am. J. Hum. Genet. 68 (1): 26–37. doi:10.1086/316954. PMC 1234923. PMID 11090341.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Nowotny M, Spiechowicz M, Jastrzebska B, et al. (2003). "Calcium-regulated interaction of Sgt1 with S100A6 (calcyclin) and other S100 proteins". J. Biol. Chem. 278 (29): 26923–8. doi:10.1074/jbc.M211518200. PMID 12746458.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.

Kategorije

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000122882 - Ensembl, maj 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000021810 - Ensembl, maj 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9928932-5] Sato T, Jigami Y, Suzuki T, Uemura H (Feb 1999). "A human gene, hSGT1, can substitute for GCR2, which encodes a general regulatory factor of glycolytic gene expression in Saccharomyces cerevisiae". Mol Gen Genet. 260 (6): 535–40. doi:10.1007/s004380050926. PMID 9928932. S2CID 28511451.

[pmid15128659-6] Gaziova I, Bonnette PC, Henrich VC, Jindra M (maj 2004). "Cell-autonomous roles of the ecdysoneless gene in Drosophila development and oogenesis". Development. 131 (11): 2715–25. doi:10.1242/dev.01143. PMID 15128659.

[entrez-7] "Entrez Gene: ECD ecdysoneless homolog (Drosophila)".

[UniProt-8] "UniProt, O95905". Pristupljeno 1. 9. 2021.

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ECD

Aminokiselinska sekvenca

Reference

Dopunska literatura

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