For faster navigation, this Iframe is preloading the Wikiwand page for CAMK1D.

CAMK1D

CAMK1D
Dostupne strukture
PDBPretraga ortologa: PDBe RCSB
Spisak PDB ID kodova

2JC6

Identifikatori
AliasiCAMK1D
Vanjski ID-jeviOMIM: 607957 MGI: 2442190 HomoloGene: 121858 GeneCards: CAMK1D
Lokacija gena (čovjek)
Hromosom 10 (čovjek)
Hrom.Hromosom 10 (čovjek)[1]
Hromosom 10 (čovjek)
Genomska lokacija za CAMK1D
Genomska lokacija za CAMK1D
Bend10p13Početak12,349,547 bp[1]
Kraj12,835,545 bp[1]
Lokacija gena (miš)
Hromosom 2 (miš)
Hrom.Hromosom 2 (miš)[2]
Hromosom 2 (miš)
Genomska lokacija za CAMK1D
Genomska lokacija za CAMK1D
Bend2|2 A1Početak5,298,268 bp[2]
Kraj5,719,326 bp[2]
Ontologija gena
Molekularna funkcija aktivnost sa transferazom
nucleotide binding
protein kinase activity
kinase activity
protein serine/threonine kinase activity
catalytic activity
ATP binding
calmodulin-dependent protein kinase activity
calmodulin binding
Ćelijska komponenta jedro
citoplazma
Biološki proces regulation of granulocyte chemotaxis
positive regulation of phagocytosis
Fosforilacija
negative regulation of apoptotic process
regulation of dendrite development
nervous system development
protein phosphorylation
positive regulation of CREB transcription factor activity
positive regulation of apoptotic process
metabolizam
inflammatory response
positive regulation of respiratory burst
positive regulation of neutrophil chemotaxis
positive regulation of neuron projection development
GO:0035404 peptidyl-serine phosphorylation
peptidyl-threonine phosphorylation
GO:0007243 intracellular signal transduction
Izvori:Amigo / QuickGO
Ortolozi
VrsteČovjekMiš
Entrez
Ensembl
UniProt
RefSeq (mRNK)

NM_020397
NM_153498
NM_001351032

NM_001290374
NM_001290375
NM_001290376
NM_177343

RefSeq (bjelančevina)

NP_065130
NP_705718
NP_001337961

NP_001277303
NP_001277304
NP_001277305
NP_796317

Lokacija (UCSC)Chr 10: 12.35 – 12.84 MbChr 2: 5.3 – 5.72 Mb
PubMed pretraga[3][4]
Wikipodaci
Pogledaj/uredi – čovjekPogledaj/uredi – miš

Kalcij/kalmodulin-ovisna protein-kinaza ID je protein koji je kod ljudi kodirangenom CAMK1D na hromosomu 10 (lokus 10p13).[5]

Aminokiselinska sekvenca

[uredi | uredi izvor]

Dužina polipeptidnog lanca iznosi 385 aminokiselina, a molekularna masa 42.914.[6]

1020304050
MARENGESSSSWKKQAEDIKKIFEFKETLGTGAFSEVVLAEEKATGKLFA
VKCIPKKALKGKESSIENEIAVLRKIKHENIVALEDIYESPNHLYLVMQL
VSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIVHRDLKPENL
LYYSQDEESKIMISDFGLSKMEGKGDVMSTACGTPGYVAPEVLAQKPYSK
AVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISD
SAKDFIRNLMEKDPNKRYTCEQAARHPWIAGDTALNKNIHESVSAQIRKN
FAKSKWRQAFNATAVVRHMRKLHLGSSLDSSNASVSSSLSLASQKDCLAP
STLCSFISSSSGVSGVGAERRPRPTTVTAVHSGSK

Funkcija

[uredi | uredi izvor]

Ovaj gen kodira člana Ca2+/kalmodulin ovisne protein-kinaze 1 potporodice serin/treonin kinaza. Kodirani protein može biti uključen u regulaciju funkcije granulocita putem transdukcije signala hemokina. Opisane su alternativno prerađene varijante transkripta koje kodiraju različite izoforme ovog gena.

Reference

[uredi | uredi izvor]
  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000183049 - Ensembl, maj 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000039145 - Ensembl, maj 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: Calcium/calmodulin-dependent protein kinase ID".
  6. ^ "UniProt, Q8IU85". Pristupljeno 30. 8. 2021.

Vanjski linkovi

[uredi | uredi izvor]
{{bottomLinkPreText}} {{bottomLinkText}}
CAMK1D
Listen to this article

This browser is not supported by Wikiwand :(
Wikiwand requires a browser with modern capabilities in order to provide you with the best reading experience.
Please download and use one of the following browsers:

This article was just edited, click to reload
This article has been deleted on Wikipedia (Why?)

Back to homepage

Please click Add in the dialog above
Please click Allow in the top-left corner,
then click Install Now in the dialog
Please click Open in the download dialog,
then click Install
Please click the "Downloads" icon in the Safari toolbar, open the first download in the list,
then click Install
{{::$root.activation.text}}

Install Wikiwand

Install on Chrome Install on Firefox
Don't forget to rate us

Tell your friends about Wikiwand!

Gmail Facebook Twitter Link

Enjoying Wikiwand?

Tell your friends and spread the love:
Share on Gmail Share on Facebook Share on Twitter Share on Buffer

Our magic isn't perfect

You can help our automatic cover photo selection by reporting an unsuitable photo.

This photo is visually disturbing This photo is not a good choice

Thank you for helping!


Your input will affect cover photo selection, along with input from other users.

X

Get ready for Wikiwand 2.0 🎉! the new version arrives on September 1st! Don't want to wait?