8A-PDHQ
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| 识别信息 | |
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| CAS号 | 131556-11-1  |
| PubChem CID | |
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| UNII | |
| CompTox Dashboard (EPA) | |
| 化学信息 | |
| 化学式 | C15H21N |
| 摩尔质量 | 215.34 g·mol−1 |
| 3D模型（JSmol） | |
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8A-PDHQ（全称：8a-苯基十氢喹啉，英語：8a-Phenyldecahydroquinoline）是一种含氮有机化合物，分子式C15H21N，可作为NMDA受体拮抗剂，1950年代由Parke-Davis开发[1][2][3]。
参考文献
[编辑]- ^ US Patent 3035059
- ^ Chen, C; Kozikowski, AP; Wood, PL; Reynolds, IJ; Ball, RG; Pang, YP. Synthesis and biological activity of 8a-phenyldecahydroquinolines as probes of PCP's binding conformation. A new PCP-like compound with increased in vivo potency.. Journal of medicinal chemistry. 1992-05-01, 35 (9): 1634–8. PMID 1315871. doi:10.1021/jm00087a020.
- ^ Elhallaoui, M; Laguerre, M; Carpy, A; Ouazzani, FC. Molecular modeling of noncompetitive antagonists of the NMDA receptor: proposal of a pharmacophore and a description of the interaction mode.. Journal of molecular modeling. 2002-02, 8 (2): 65–72. PMID 12032600. doi:10.1007/s00894-001-0067-4.
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