香柑内酯
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| 臨床資料 | |
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| 给药途径 | 口服 |
| ATC碼 | |
| 法律規範狀態 | |
| 法律規範 |
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| 识别信息 | |
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| CAS号 | 484-20-8 |
| PubChem CID | |
| ChemSpider | |
| UNII | |
| KEGG | |
| ChEMBL | |
| CompTox Dashboard (EPA) | |
| ECHA InfoCard | 100.006.913 |
| 化学信息 | |
| 化学式 | C12H8O4 |
| 摩尔质量 | 216.19 g/mol |
| 3D模型（JSmol） | |
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香柑内酯（5-甲氧补骨脂素）是一种存在于香柠檬精油与其他柑橘属植物精油[1]，以及葡萄柚汁中的呋喃香豆素 （furanocoumarin），属补骨脂素的衍生物。[2] 它是香柠檬精油中引起光敏性（光毒性）的活性物质。[3] 目前市面上的香水采用的是不含香柑内酯的香柠檬精油或人工合成的类似香味物质。
医学上香柑内酯与长波紫外线（UVA）一同用于银屑病的長波紫外線光化治療。[4][5]
参考资料
[编辑]- ^ Calvarano I., Calvarano M., Gionfriddo F., Bovalo F., Postorino E. HPLC profile of citrus essential oils from different species and geographic origin. Essenze Derivati agrumari. 1995, 65: 488–502.
- ^ Sakamaki N., Nakazato M., Matsumoto H., Hagino K., Hirata K., Ushiyama H. Contents of furanocoumarins in grapefruit juice and health foods. Journal of the Food Hygienic Society of Japan. 2008, 49 (4): 326–331. PMID 18787320. doi:10.3358/shokueishi.49.326.
- ^ Francesco Gionfriddo, Enrico Postorino and Giuseppe Calabrò. Elimination of Furocoumarins in Bergamot Peel Oil. Perfumer & Flavorist. 2004, 29.
- ^ HONIGSMANN, HERBERT; JASCHKE, ERNA; GSCHNAIT, FRITZ; BRENNER, WILHELM; FRITSCH, PETER; WOLFF, KLAUS. 5-Methoxypsoralen (Bergapten) in photochemotherapy of psoriasis. British Journal of Dermatology (Wiley-Blackwell). 1979, 101 (4): 369–378. ISSN 0007-0963. doi:10.1111/j.1365-2133.1979.tb00014.x.
- ^ A. Tanew, B. Ortel, K. Rappersberger, H. Hönigsmann. 5-Methoxypsoralen (Bergapten) for photochemotherapy. Bioavailability, phototoxicity, and clinical efficacy in psoriasis of a new drug preparation. Journal of the American Academy of Dermatology. 1988-2, 18 (2 Pt 1): 333–338 [2019-05-25]. ISSN 0190-9622. PMID 3279089.
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