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表型混合

表型混合(英文:Phenotype mixing)是两种含有不同基因材料病毒之间的非遗传性交互。当两个病毒感染同一细胞时,在病毒复制英语Viral replication过程中,一个病毒的基因组可能和另一个病毒的衣壳进行组装,或者与同时拥有不同来源表面蛋白的衣壳进行组装,这被称为表型混合。[1][2] 换句话说,子代病毒颗粒将同时拥有两种原始病毒的成分:基因组来自其中一个原始病毒,而表面蛋白完全或部分来自另一种原始病毒。[1][2]

表型混合最早在噬菌体中被观察到,此后在脊髓灰质炎病毒等病毒中也被发现。[1]

参考资料

[编辑]
  1. ^ 1.0 1.1 1.2 Burge, B. W.; Pfefferkorn, E. R. Phenotypic Mixing between Group A Arboviruses. Nature. 1966-06, 210 (5043): 1397–1399. ISSN 1476-4687. doi:10.1038/2101397a0 (英语). 
  2. ^ 2.0 2.1 Viral Genetics. www.microbiologybook.org. [2021-04-02]. (原始内容存档于2021-01-03). 
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表型混合
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