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玛丽莲·科扎克

玛丽莲·科扎克
出生 (1943-07-08) 1943年7月8日81歲)
 美国俄亥俄州阿克伦
国籍 美国
母校约翰斯·霍普金斯大学
知名于Kozak序列
科学生涯
研究领域微生物学分子生物學
机构羅格斯大學罗伯特伍德强生医学院英语Robert Wood Johnson Medical School
博士導師丹尼爾·那森斯
其他指导者艾倫·夏特金英语Aaron Shatkin

玛丽莲·科扎克(英語:Marilyn S. Kozak,1943年7月8日)是美國的生化學家、羅格斯大學罗伯特伍德强生医学院英语Robert Wood Johnson Medical School教授。科扎克於约翰斯·霍普金斯大学獲微生物學博士學位,指導教授為丹尼爾·那森斯,研究主題是MS2噬菌體英语Bacteriophage MS2[1][2]。畢業後她任教於匹茲堡大學生物學系,研究真核生物轉譯的起始機制,發表了轉譯起始所需的Kozak序列[3][4][5]。後來科札克於紐澤西醫科與牙科大學英语University of Medicine and Dentistry of New Jersey任教授,在2013年該大學併入羅格斯大學後成為羅格斯大學罗伯特伍德强生医学院教授。

科札克曾於80年代被《科學家英语The Scientist (magazine)》雜誌依論文引用數選為「十大女性科學家」之一[3]

參考文獻

  1. ^ Kozak, M; Nathans, D. Translation of the genome of a ribonucleic acid bacteriophage.. Bacteriological Reviews. March 1972, 36 (1): 109–34. PMC 378432可免费查阅. PMID 4555183. doi:10.1128/MMBR.36.1.109-134.1972. 
  2. ^ Kozak, M; Nathans, D. Differential inhibition of coliphage MS2 protein synthesis by ribosome-directed antibiotics.. Journal of Molecular Biology. 1972-09-14, 70 (1): 41–55. PMID 4561347. doi:10.1016/0022-2836(72)90162-3. 
  3. ^ 3.0 3.1 Grissom, Abigail. Research: Top 10 Women Scientists Of The '80s: Making A Difference. The Scientist. 1990-10-15 [2015-07-04]. (原始内容存档于2015-07-04). 
  4. ^ Kozak, M. An analysis of 5'-noncoding sequences from 699 vertebrate messenger RNAs.. Nucleic Acids Research. 1987-10-26, 15 (20): 8125–48. PMC 306349可免费查阅. PMID 3313277. doi:10.1093/nar/15.20.8125. 
  5. ^ Kozak, M. Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes.. Cell. 1986-01-31, 44 (2): 283–92. PMID 3943125. S2CID 15613863. doi:10.1016/0092-8674(86)90762-2. 
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玛丽莲·科扎克
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