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己酸诺龙

己酸诺龙
臨床資料
商品名（英语：Drug nomenclature）Anabolin Depot
其他名稱Nandrolone hexanoate; 19-Nortestosterone 17β-hexanoate; 17β-((1-Oxohexyl)oxy)estr-4-en-3-one
给药途径Intramuscular injection
藥物類別（英语：Drug class）Androgen; Anabolic steroid; Androgen ester; Progestogen
识别信息
  • [(8R,9S,10R,13S,14S,17S)-13-methyl-3-oxo-2,6,7,8,9,10,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl] hexanoate
CAS号52230-62-3
PubChem CID
ChemSpider
CompTox Dashboard（英语：CompTox Chemicals Dashboard） (EPA)
化学信息
化学式C24H36O3
摩尔质量372.55 g·mol−1
3D模型（JSmol（英语：JSmol））
  • CCCCCC(=O)O[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4=CC(=O)CC[C@H]34)C
  • InChI=1S/C24H36O3/c1-3-4-5-6-23(26)27-22-12-11-21-20-9-7-16-15-17(25)8-10-18(16)19(20)13-14-24(21,22)2/h15,18-22H,3-14H2,1-2H3/t18-,19+,20+,21-,22-,24-/m0/s1
  • Key:SBKWVCUBCYGVKF-XFIIBVRQSA-N

己酸诺龙（英語：nandrolone hexanoate或Nandrolone caproate，或称为19-去甲睾酮-17β-己酸酯 19-nortestosterone 17β-caproate，商品名为Anabolin Depot）是一种雄激素同化類固醇（AAS）药物。[1][2][3]

19-去甲睾酮（Nandrolone，诺龙），己酸诺龙的最终活性形式

参考文献

[编辑]
  1. ^ J. Elks. The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. 14 November 2014: 660–. ISBN 978-1-4757-2085-3. 
  2. ^ Index Nominum 2000: International Drug Directory. Taylor & Francis. January 2000: 716–717. ISBN 978-3-88763-075-1. 
  3. ^ I.K. Morton; Judith M. Hall. Concise Dictionary of Pharmacological Agents: Properties and Synonyms. Springer Science & Business Media. 6 December 2012. ISBN 978-94-011-4439-1. 
受体
AR (A, B)


注意：此处包括了那些只有微弱男性化效应（或抗男性化（如氧雄龙））的蛋白同化甾类（因为它们合成代谢效应也是通过激活雄激素受体而是显得）。

  • Mixed (SARMs): AC-262,356
  • Andarine
  • BMS-564,929
  • Enobosarm
  • LGD-2226
  • LGD-3303
  • S-23
  • S-40503
酶
(抑制剂)
  • 22-ABC
  • 3,3′-Dimethoxybenzidine
  • 3-Methoxybenzidine
  • Aminoglutethimide
  • Cyanoketone
  • Danazol
  • Etomidate
  • Mitotane
  • Trilostane
3β-HSD (I, II)
17β-HSD (I-XIV)
  • Danazol
  • Simvastatin
5α還原酶 (I, II)
  • 22-Oxime
  • Alfatradiol
  • Azelaic acid
  • β-Sitosterol
  • Bexlosteride
  • Dutasteride
  • 表睾酮
  • Epristeride
  • Finasteride
  • Izonsteride
  • L-39
  • Lapisteride
  • Polyunsaturated fatty acids (α-linolenic acid, linoleic acid, γ-linolenic acid, oleic acid)
  • Turosteride
  • Vitamin B6
  • 锌
  • 1,4,6-Androstatriene-3,17-dione
  • 4-Androstene-3,6,17-trione
  • 4-Cyclohexylaniline
  • 4-Hydroxytestosterone
  • 5α-DHNET
  • Abyssinone II
  • Aminoglutethimide
  • Anastrozole
  • 抗坏血酸（维生素C）
  • Atamestane
  • Bifonazole
  • CGP-45,688
  • CGS-47,645
  • Clotrimazole
  • 双氢睾酮
  • Difeconazole
  • Econazole
  • Exemestane
  • Fadrozole
  • Fenarimol
  • Finrozole
  • Formestane
  • Imazalil
  • Isoconazole
  • Ketoconazole
  • Letrozole
  • Liarozole
  • MEN-11066
  • Miconazole
  • Minamestane
  • Nimorazole
  • NKS01
  • ORG-33,201
  • Penconazole
  • Plomestane
  • Prochloraz
  • Propioconazole
  • Pyridoglutethimide
  • Rogletimide
  • Rotenone
  • Talarozole
  • Testolactone
  • Tioconazole
  • Triadimefon
  • Triadimenol
  • Troglitazone
  • Vorozole
  • YM511
  • 锌

Note: 21-Hydroxylase inhibitors may also affect androgen levels as they prevent metabolism of androgen steroid precursors.

其他
间接
  • Estrogens/Antiestrogens (see here)
  • GnRH agonists/antagonists (see here)
  • Gonadotropins/Antigonadotropins (see here)
  • Plasma proteins (SHBG, ABP, Albumin)
  • Progestogens/Antiprogestins (see here)
  • Prolactin
分类
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己酸诺龙
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