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己酸诺龙 .
己酸诺龙 商品名 Anabolin Depot 其他名稱 Nandrolone hexanoate; 19-Nortestosterone 17β-hexanoate; 17β-((1-Oxohexyl)oxy)estr-4-en-3-one 给药途径 Intramuscular injection 藥物類別 Androgen ; Anabolic steroid; Androgen ester; Progestogen
[(8R ,9S ,10R ,13S ,14S ,17S )-13-methyl-3-oxo-2,6,7,8,9,10,11,12,14,15,16,17-dodecahydro-1H -cyclopenta[a ]phenanthren-17-yl] hexanoate
CAS号 52230-62-3 PubChem CID ChemSpider CompTox Dashboard (EPA ) 化学式 C 24 H 36 O 3 摩尔质量 372.55 g·mol−1 3D模型(JSmol )
CCCCCC(=O)O[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4=CC(=O)CC[C@H]34)C
InChI=1S/C24H36O3/c1-3-4-5-6-23(26)27-22-12-11-21-20-9-7-16-15-17(25)8-10-18(16)19(20)13-14-24(21,22)2/h15,18-22H,3-14H2,1-2H3/t18-,19+,20+,21-,22-,24-/m0/s1
Key:SBKWVCUBCYGVKF-XFIIBVRQSA-N
己酸诺龙 (英語:nandrolone hexanoate 或Nandrolone caproate,或称为19-去甲睾酮-17β-己酸酯 19-nortestosterone 17β-caproate,商品名 为Anabolin Depot)是一种雄激素 同化類固醇 (AAS)药物 。[ 1] [ 2] [ 3]
19-去甲睾酮 (Nandrolone,诺龙 ),己酸诺龙的最终活性形式
^ J. Elks. The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies . Springer. 14 November 2014: 660–. ISBN 978-1-4757-2085-3 .
^ Index Nominum 2000: International Drug Directory . Taylor & Francis. January 2000: 716–717. ISBN 978-3-88763-075-1 .
^ I.K. Morton; Judith M. Hall. Concise Dictionary of Pharmacological Agents: Properties and Synonyms . Springer Science & Business Media. 6 December 2012. ISBN 978-94-011-4439-1 .
受体
酶 (抑制剂 )
22-ABC
3,3′-Dimethoxybenzidine
3-Methoxybenzidine
Aminoglutethimide
Cyanoketone
Danazol
Etomidate
Mitotane
Trilostane
3β-HSD (I, II)
17β-HSD (I-XIV)
22-Oxime
Alfatradiol
Azelaic acid
β-Sitosterol
Bexlosteride
Dutasteride
表睾酮
Epristeride
Finasteride
Izonsteride
L-39
Lapisteride
Polyunsaturated fatty acids (α-linolenic acid, linoleic acid, γ-linolenic acid, oleic acid)
Turosteride
Vitamin B6
锌
1,4,6-Androstatriene-3,17-dione
4-Androstene-3,6,17-trione
4-Cyclohexylaniline
4-Hydroxytestosterone
5α-DHNET
Abyssinone II
Aminoglutethimide
Anastrozole
抗坏血酸 (维生素C )
Atamestane
Bifonazole
CGP-45,688
CGS-47,645
Clotrimazole
双氢睾酮
Difeconazole
Econazole
Exemestane
Fadrozole
Fenarimol
Finrozole
Formestane
Imazalil
Isoconazole
Ketoconazole
Letrozole
Liarozole
MEN-11066
Miconazole
Minamestane
Nimorazole
NKS01
ORG-33,201
Penconazole
Plomestane
Prochloraz
Propioconazole
Pyridoglutethimide
Rogletimide
Rotenone
Talarozole
Testolactone
Tioconazole
Triadimefon
Triadimenol
Troglitazone
Vorozole
YM511
锌
Note: 21-Hydroxylase inhibitors may also affect androgen levels as they prevent metabolism of androgen steroid precursors.
其他
间接
Estrogens/Antiestrogens (see here)
GnRH agonists/antagonists (see here )
Gonadotropins/Antigonadotropins (see here )
Plasma protein s (SHBG, ABP, Albumin)
Progestogens/Antiprogestins (see here )
Prolactin
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